Results 61 to 70 of about 84,446 (125)

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Resveratrol ameliorates atherosclerosis induced by high-fat diet and LPS in ApoE−/− mice and inhibits the activation of CD4+ T cells

Nutrition & Metabolism, 2020
Background Atherosclerosis (AS), which characterized with the accumulation of lipids on the vessel wall, is the pathological basis of many cardiovascular diseases (CVD) and seriously threatens human health.
Liyu Zhou, Jun Long, Yuting Sun, Weikai Chen, Runze Qiu, Dongping Yuan   +5 more
doaj   +1 more source

Purpurin Alleviates Chemotherapy‐Induced Thrombocytopenia Through Estrogen Receptor α Dependent Phosphoinositide 3‐Kinase/Protein Kinase B Signalling

Phytotherapy Research, EarlyView.
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan, Xinle Wang, Lu Hao, Xiaoqin Tang, Zhixuan Liu, Long Wang, Xiang Xie, Xiang Li, Chunling Zhao, Yan Li, Xinwu Huang, Yuanzhi Liu, Jianming Wu   +12 more
wiley   +1 more source

Dihydrotanshinone I Targets MIF to Inhibit GSK‐3β/β‐Catenin Axis‐Mediated Invasion and Metastasis in Gastric Cancer

Phytotherapy Research, EarlyView.
DHT directly binds to MIF and subsequently blunts AKT signaling, which restores the kinase activity of GSK‐3β. The reactivated GSK‐3β then promotes the phosphorylation (Ser33/37/Thr41) and proteasomal degradation of β‐catenin, thereby preventing its nuclear translocation and inhibiting the transcription of EMT‐related genes (e.g., Snail and Twist ...
Chuhang Wang, Xiaochen Ni, Yuyan Pan, Wei Fan, Jianing Guo, Kaiyuan Zhang, Mingsi Zhang, Linfeng Zheng, Yunhai Wei, Tao Jiang, Guangji Zhang   +10 more
wiley   +1 more source

Lectures.

, 1890
[v.1] Series of twelve lectures on pharmacy by C.S.N. Hallberg.--[v.2] Lectures on botany and materia medica by E.S. Bastin.--[v.3] Lectures on chemistry by C.S.
National Institute of Pharmacy (U.S.)
core  

From the Greek Medical Manuscripts of the Ottoman Empire to the Pharmacopoeia I of the Greek State: Pharmacy and Political Change in Southeastern Europe [PDF]

, 2023
The article studies the transition from the medical manuscripts that circulatedas a means of knowledge preservation and professional regulation in the early modernGreek world to the first edited pharmacopoeia of the Greek state in 1837.
Seirinidou, Vaso, Seriatou, Penelope, Barlagiannis , Athanasios   +2 more
core  

A dual‐responsive fluorescent probe for imaging viscosity and polarity in nonalcoholic fatty liver disease

Smart Molecules, EarlyView.
We developed a BODIPY‐based fluorescent probe with dual responsiveness to viscosity and polarity, enabling sensitive and precise imaging of non‐alcoholic fatty liver disease. Abstract Viscosity and polarity are critical physiological parameters implicated in the onset and progression of nonalcoholic fatty liver disease (NAFLD).
Di Zhao, Zhizhong Wang, Ke Xu, Yuntai Liu, Di Wu, Ting Jiang, Haonan Gao, Chengmei Xiao, Debin Zheng, Kai Wang, Wenhao Zhai   +10 more
wiley   +1 more source

Conference Report: Materia Medica on the Move, Leiden, 15-17 April 2015

, 2015
By Sietske Fransen What happens if you put together historians of early modern science and medicine, ethnobotanists, historians of pharmacy, and art historians in the Dutch National Biodiversity Center in Leiden?
Sietske Fransen
core  

Polyphyllin I exerts anti-hepatocellular carcinoma activity by targeting ZBTB16 to activate the PPARγ/RXRα signaling pathway

Chinese Medicine
Background Studies have reported that polyphyllin I (PPI) had effective anti-tumor activity against hepatocellular carcinoma (HCC). However, the precise molecular mechanism of this action and the direct target remain unclear. The aim of this study was to
Lu shan, Yijun Chen, Guo An, Xiaoyu Tao, Chuanqi Qiao, Meilin Chen, Jiaqi Li, Ruichao Lin, Jiarui Wu, Chongjun Zhao   +9 more
doaj   +1 more source

Phenolic exudates from orchid seeds as nutrients chemically attract fungi

Journal of Integrative Plant Biology, EarlyView.
Most orchid species require fungi for natural germination, but the molecular mechanism of this symbiosis is poorly understood. Cremastra appendiculata seeds secrete phenolic acids before fungal contact, acting as nutrient molecules to chemically attract its symbiotic fungus Coprinellus disseminatus.
Zhao Liu, Yan‐Duo Wang, Bo Xiao, Chao‐Qun Xu, Yuan Chen, Kai‐Peng Liu, Xiao‐Hong Zhao, Jian Yang, Jun‐Feng Niu, Xiao‐Ke Xing, Gang Ding   +10 more
wiley   +1 more source