Results 81 to 90 of about 88,549 (174)

Effects of Total Flavonoids From Rubus chingii Hu on the Hypothalamic–Pituitary–Ovarian Axis and Inflammatory Response in Polycystic Ovary Syndrome Rats

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
RHF improves sex hormone secretion imbalance, restores the estrous cycle, inhibits ovarian hyperplasia and pathology, and reduces systemic and local ovarian inflammation in PCOS rats via enhancing HPO axis function and suppressing NLRP3 inflammasome signaling pathway activation.
Mengfan Peng, Baosong Liu, Lanyue Cao, Chuan Rao, Yingying Sun, Caixia Li, Hao Chen, Lei Yang   +7 more
wiley   +1 more source

Current application of metabolomics in the elucidation of processing mechanisms used in Chinese materia medica: A review

, 2020
Processing, a key characteristic of traditional Chinese medicine (TCM), enhances the efficacy and safety of Chinese materia medica (CMM) in clinics. It plays an important role in TCM.
Lei, Yutian, Jiang, Guihua, Huang, Ting, Zhang, Yanfei, Jiang, Yunbin   +4 more
core   +1 more source

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

iMetaMed, Volume 2, Issue 2, June 2026.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian, Shuyu Xie, Yanqing Tang, Junjie Liang, Wenhan Zhu, Tianqi Liu, Yewen Sun, Yang Yang, Luoxi Zhang, Danfeng Wang, Chuyao Lin, Jinyu Jia, Minjia Tan, Jun‐Yu Xu   +13 more
wiley   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode, Mitchel C. Rothholz, Stephan L. Foster, Erica R. Brody, John D. Gräbenstein   +4 more
wiley   +1 more source

Conference Report: Materia Medica on the Move, Leiden, 15-17 April 2015

, 2015
By Sietske Fransen What happens if you put together historians of early modern science and medicine, ethnobotanists, historians of pharmacy, and art historians in the Dutch National Biodiversity Center in Leiden?
Sietske Fransen
core  

Quelques éléments de la matière médicale arabe d'après des sceaux de verre de la première moitié du VIIIe siècle : Sami K. Hamarneh, Henry A. Awad, Arabic glass seals on early eight-century containers for materia medica. Pharmacy in History, 18, 1976, n° 3,

, 1977
Julien Pierre. Quelques éléments de la matière médicale arabe d'après des sceaux de verre de la première moitié du VIIIe siècle : Sami K. Hamarneh, Henry A. Awad, Arabic glass seals on early eight-century containers for materia medica.
Julien, Pierre
core   +1 more source

Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis

Frontiers in Genetics, 2018
Background and Objective: Non-small cell lung cancer (NSCLC) accounts for 80–85% of all patients with lung cancer and 5-year relative overall survival (OS) rate is less than 20%, so that identifying novel diagnostic and prognostic biomarkers is urgently ...
Mengwei Ni, Xinkui Liu, Jiarui Wu, Dan Zhang, Jinhui Tian, Jinhui Tian, Ting Wang, Shuyu Liu, Ziqi Meng, Kaihuan Wang, Xiaojiao Duan, Wei Zhou, Xiaomeng Zhang   +12 more
doaj   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Progress in Natural Products Target Discovery Technology

MedComm, Volume 7, Issue 6, June 2026.
Here, we provide a comprehensive overview of current technologies and recent advancements in therapeutic target discovery for natural products. By systematically synthesizing the principles, methodologies, and practical applications of existing experimental and computational strategies, this work provides a more actionable reference framework for ...
Qiyuan Pan, Xiao Yuan, Jinmei Jin, Xin Luan, Cheng Luo, Hongzhuan Chen, Weidong Zhang, Hao Zhang   +7 more
wiley   +1 more source