Results 101 to 110 of about 94,243 (174)

Inhibition of FAK promotes pancreatic cancer immunotherapy by mediating CXCL10 secretion to enhance CD8+ T cell infiltration

OncoImmunology
Immunotherapy has demonstrated potential in treating various malignant tumors, but its efficacy in pancreatic cancer (PC) remains limited, possibly due to the dense stromal components and immunosuppressive microenvironment of PC.
Yu-Chen Shi, Qingling An, Na Tang, Yong-Qiang Zhang, Shu-Qiao Xing, Fan Song, Xiao-Qiang Li   +6 more
doaj   +1 more source

Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α–DSG2 signaling

Experimental and Molecular Medicine
s Circulating tumor cell (CTC) clusters, key in metastasis, rely on intercellular junctions for stability. However, the specific mechanisms governing intercellular connections within CTC clusters and the strategy targeting intercellular junctions to ...
Jueyao Zou, Junfeng Shi, Qiong Chen, Ziyan Zhu, Tongyao Hu, Zhengyu Zhang, Zhiqiang Pan, Fei Xu, Yong Zhu, Yuanyuan Wu, Yang Zhao, Aiyun Wang, Yin Lu, Yanhong Pan, Wenxing Chen   +14 more
doaj   +1 more source

Correction: Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking

Chinese Medicine, 2023
Yingying Tan, Fanqin Zhang, Xiaotian Fan, Shan Lu, Yingying Liu, Zhishan Wu, Zhihong Huang, Chao Wu, Guoliang Cheng, Bing Li, Jiaqi Huang, Antony Stalin, Wei Zhou, Jiarui Wu   +13 more
doaj   +1 more source

Acetoacetate Ameliorates Hepatic Fibrosis by Targeting Peroxisome Proliferator-Activated Receptor Gamma to Restore Lipid Droplets in Activated Hepatic Stellate Cells

Pharmaceuticals
Background: Hepatic fibrosis (HF) is a progressive liver disease characterized by the activation of hepatic stellate cells (HSCs) and changes in lipid metabolism.
Ya Zhou, Feixia Wang, Mengru Hu, Siwei Xia, Yang Li, Shizhong Zheng, Feng Zhang   +6 more
doaj   +1 more source

L’usage des lichens : Mitchell (Michael E .), “ Contentious Cures : The rise and Decline of Lichens as European Materia Medica”, (“Usage médical controversé : l’émergence et le déclin de l’utilisation des lichens pour la matière médicale en Europe”), Pharmacy in History, 57, n° 3-4, 2015

, 2016
Bonnemain Bruno. L’usage des lichens : Mitchell (Michael E .), “ Contentious Cures : The rise and Decline of Lichens as European Materia Medica”, (“Usage médical controversé : l’émergence et le déclin de l’utilisation des lichens pour la matière médicale
Bonnemain, Bruno
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Clinical simulations using virtual patient avatars for pre-registration pharmacist training: a mixed methods evaluation [PDF]

, 2018
Virtual patients (VPs) are routinely used in the training of medicine and nursing professionals but uptake into pharmacy has been slower. The pharmacy pre-registration training year takes place in the workplace and a disparity in the perceptions of ...
Thompson, Jessica
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Scienza medica e tradizione enciclopedica nell'Inghilterra del Settecento : testi a confronto [PDF]

, 2002
Obiettivo di questo articolo è la descrizione del modo in cui la scienza medica viene presentata nelle tre enciclopedie settecentesche inglesi: il Lexicon Technicum (1704) di John Harris, la Cyclopaedia (1728) di Ephraim Chambers e l’Encyclopaedia ...
E. Lonati
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Synergistic effects of ferulic acid and wogonin on cholestatic liver injury via gut microbiota modulation

npj Biofilms and Microbiomes
Cholestasis, a bile flow disorder common to many liver diseases, currently lacks effective treatments. Emerging evidence links gut microbiota disturbances to cholestatic liver injury.
Xin Luo, Ting Mao, Xi Wang, Peng Cheng, Mingyuan Liu, Ruizhi Tao, Feihui Wang, Lizhi Zhao, Yunlong Shan, Yin Lu, Zhonghong Wei   +10 more
doaj   +1 more source

Two previously undescribed triterpenoid saponins from the roots and rhizomes of Caulophyllum robustum Maxim

Frontiers in Chemistry
Since ancient times, plants have provided humans with important bioactive compounds for the treatment of various diseases. Nine compounds were isolated from the roots and rhizomes of Caulophyllum robustum (a plant in the family Panaxaceae), including two
Cong-Yu Zhang, Yu-Mei Wang, Peng-Cheng Qiu, Jia-Yu Feng, Bing-Wen Wang, Yu Cao, Yi-Sha Wei, Yi-Tong Zhou, Hai-Feng Tang, Yun-Yang Lu, Qian Zhang   +10 more
doaj   +1 more source

How medicine could have developed differently: A Tory historiographical analysis of the conflict between allopathic and homoeopathic medicine in America and Britain from 1870 to 1920. [PDF]

, 2007
After its formulation by Samuel Hahnemann (1755-1843) at the end of the 18th century, homoeopathy spread to Britain and America in the 1820ร. Based upon the principle or law of "similia similibus curentur"- let like be cured by like-homoeopathy presented
Brierley-Jones, Lynda Karen
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