Results 21 to 30 of about 88,549 (174)

Factors influencing the commissioning and provision of community pharmacy Emergency Hormonal Contraception services in England [PDF]

, 2022
In England, community pharmacies provide services commissioned either nationally or locally. Local commissioning exhibits variation in specification and implementation, exemplified by Emergency Hormonal Contraception (EHC) services.
Thayer, Nicholas Mark
core  

The Decline and Fall of Materia Medica and the Rise of Pharmacology and Therapeutics in Veterinary Medicine

, 2022
International audienceMateria Medica is a Latin term, relating to the history of pharmacy. It describes the sources (vegetable, animal and mineral), nature, preparation, and properties of substances or mixtures of substances, which were used as remedies ...
Toutain, Pierre-Louis, Lees, Peter, Bäumer, Wolfgang   +2 more
core   +1 more source

Tanshinone IIA attenuates the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis

Experimental Hematology & Oncology, 2022
Background Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear.
Xiaoman Li, Qi Jia, Yinyin Zhou, Xuan Jiang, Li Song, Yuanyuan Wu, Aiyun Wang, Wenxing Chen, Shijun Wang, Yin Lu   +9 more
doaj   +1 more source

GCIP attenuates DOCA/salt-induced cardiac hypertrophy and fibrosis in mice

Di-san junyi daxue xuebao, 2022
Objective To determine the effects of improvement of G alpha q-protein carboxyl terminus imitation polypeptide (GCIP) on deoxycorticosterone acetate (DOCA)/salt-induced cardiac hypertrophy and fibrosis in mice.
TANG Kecheng, LIU Qiao, YANG Shengqian, ZHONG Bin, LUO Qingman, LI Xiaohui   +5 more
doaj   +1 more source

Pharmacy and Materia Medica

, 1940
openaire   +2 more sources

Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments

Chinese Medicine, 2023
Background Pancreatic cancer is one of the most lethal cancers worldwide. Aidi injection (ADI) is a representative antitumor medication based on Chinese herbal injection, but its antitumor mechanisms are still poorly understood.
Haojia Wang, Zhishan Wu, Xiaotian Fan, Chao Wu, Shan Lu, Libo Geng, Antony Stalin, Yingli Zhu, Fanqin Zhang, Jiaqi Huang, Pengyun Liu, Huiying Li, Leiming You, Jiarui Wu   +13 more
doaj   +1 more source

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

Nature Communications, 2018
The metabolic regulator protein family, mTOR, regulate natural killer (NK) cell development and function, but the underlying mechanism is unclear. Here, the authors show that Raptor/mTORC1 and Rictor/mTORC2 form a feedback crosstalk network to variegate ...
Fangjie Wang, Meng Meng, Banghui Mo, Yao Yang, Yan Ji, Pei Huang, Wenjing Lai, Xiaodong Pan, Tingting You, Hongqin Luo, Xiao Guan, Yafei Deng, Shunzong Yuan, Jianhong Chu, Michael Namaka, Tiffany Hughes, Lilin Ye, Jianhua Yu, Xiaohui Li, Youcai Deng   +19 more
doaj   +1 more source

Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy

Angewandte Chemie, EarlyView.
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng, Haiyan Zhou, Wang Xia, Hongxiang Wu, Xuechen Li   +4 more
wiley   +2 more sources

A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence

Frontiers in Pharmacology, 2020
Clinically, the treatments against asthma like β2 agonist focus on controlling the symptoms rather than inhibiting recurrence radically. This study aims to evaluate the efficacy and mechanism of a potent Chinese prescription Yu-Ping-Feng-San (YPFS ...
Kaifan Bao, Weiyuan Yuan, Yijing Zhou, Yanyan Chen, Xuerui Yu, Xiaoyu Wang, Zhirong Jia, Xi Yu, Xiaotong Wang, Lu Yao, Siqi Wang, Yifan Xu, Yuheng Zhang, Jie Zheng, Min Hong   +14 more
doaj   +1 more source

Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder

Cell Communication and Signaling, 2023
The association between capsaicin, the major natural pungent compound of chili peppers, and gastric cancer progression has engendered conflicting findings.
Rui Deng, Suyun Yu, Xingqiu Ruan, Huan Liu, Gangfan Zong, Peng Cheng, Ruizhi Tao, Wenxing Chen, Aiyun Wang, Yang Zhao, Zhonghong Wei, Yin Lu   +11 more
doaj   +1 more source