Results 31 to 40 of about 94,376 (172)

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis

Cell Death and Disease, 2021
Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disorder characterized by recurrent eczematous lesions. Interleukin (IL)−33, a cytokine of the IL-1 family, was found to play an important role in the pathogenesis of AD.
Jie Zheng, Lu Yao, Yijing Zhou, Xiaoqun Gu, Can Wang, Kaifan Bao, Yang Sun, Min Hong   +7 more
doaj   +1 more source

Revealing the Mechanism of Huazhi Rougan Granule in the Treatment of Nonalcoholic Fatty Liver Through Intestinal Flora Based on 16S rRNA, Metagenomic Sequencing and Network Pharmacology

Frontiers in Pharmacology, 2022
Graphical ...
Yingying Liu, Yingying Tan, Jiaqi Huang, Chao Wu, Xiaotian Fan, Antony Stalin, Shan Lu, Haojia Wang, Jingyuan Zhang, Fanqin Zhang, Zhishan Wu, Bing Li, Zhihong Huang, Meilin Chen, Guoliang Cheng, Yanfang Mou, Jiarui Wu   +16 more
doaj   +1 more source

Old School Catalog 1921-22, The School of Pharmacy [PDF]

, 1921
https://scholar.valpo.edu/oldschoolcatalogs/1089/thumbnail ...
Valparaiso University
core   +2 more sources

Synthesis and Biological Evaluation of Ginsenoside Compound K Derivatives as a Novel Class of LXRα Activator

Molecules, 2017
Compound K is one of the active metabolites of Panaxnotoginseng saponins, which could attenuate the formation of atherosclerosis in mice modelsvia activating LXRα.
Yan Huang, Hongmei Liu, Yingxian Zhang, Jin Li, Chenping Wang, Li Zhou, Yi Jia, Xiaohui Li   +7 more
doaj   +1 more source

Old School Catalog 1912-13, Chicago College of Medicine and Surgery [PDF]

, 1912
https://scholar.valpo.edu/oldschoolcatalogs/1010/thumbnail ...
Valparaiso University
core   +1 more source

Based on Systematic Pharmacology: Molecular Mechanism of Siwei Jianbu Decoction in Preventing Oxaliplatin-Induced Peripheral Neuropathy

Neural Plasticity, 2020
Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect caused by chemotherapy drugs, and its existence seriously affects the quality of life of patients.
Peng Zhang, Yuting Lu, Chao Yang, Qiuyan Zhang, Yangyan Qian, Jinshuai Suo, Peng Cheng, Jing Zhu   +7 more
doaj   +1 more source

Materia Medica and Pharmacy.

JAMA: The Journal of the American Medical Association, 1906
Mode of access: Internet.
openaire   +2 more sources

Lichens Mentioned by Pedanios Dioscorides [PDF]

, 2012
Lichens are included in the classification system of fungi and have been used in medicine, pharmacy and industry from antiquity to present day in the treatment of various diseases.
Yavuz, Mustafa
core  

Cereals of antiquity and early Byzantine times. Wheat and barley in medical sources (second to seventh centuries AD) [PDF]

, 2014
The present book aims at a detailed analysis of the evolution of dietetic doctrines and an assessment of the value of medical sources for historians of food.
Jagusiak, Krzysztof, Kokoszko, Maciej, Rzeźnicka, Zofia   +2 more
core   +1 more source