Results 111 to 120 of about 311,374 (311)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Scaffolding patient counselling skills in Australian university pharmacy programs. [PDF]
This paper presents the results of an appraisal of the extent of, and approaches to, scaffolding for development of counseling skills of pharmacy students across Australian universities. There were two stages in the work.
McKauge, Leigh +4 more
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Developing a Pharmacy Professional Elective Course: Underserved Populations [PDF]
Objectives. To ascertain the current curriculum exposure, knowledge, and interest in medically underserved populations of 3rd and 4th year professional pharmacy students enrolled at Butler University. Methods.
Hedrick, Courtney Ann
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
In recent years, nuts have gained importance because of their nutritional benefits in promoting health and preventing chronic diseases. Despite their recognized role as part of healthy dietary patterns, global consumption is below recommended levels ...
Ivana Stević +6 more
doaj +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Bukoli Brian,1 Narayana Goruntla,1 Bhavana Reddy Bommireddy,2 Bhavani M Mopuri,2 Vigneshwaran Easwaran,3 Mohammad Jaffar Sadiq Mantargi,4 Durga Prasad Thammisetty,5 Sarad Pawar Naik Bukke,6 Tadele Mekuriya Yadesa,1 Ebere Emilia Ayogu7 1Department of ...
Brian B +9 more
doaj
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Barriers to medication counselling for people with mental health disorders: a six country study
Provision of medication information may improve adherence and prevent medication related problems. People with mental health disorders commonly receive less medication counselling from pharmacists than people with other common long term and persistent ...
Aaltonen SE +10 more
doaj

