Results 121 to 130 of about 3,203,915 (312)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Strong stability of Nash equilibria in load balancing games [PDF]

open access: yes
We study strong stability of Nash equilibria in the load balancing games of m (m >= 2) identical servers, in which every job chooses one of the m servers and each job wishes to minimize its cost, given by the workload of the server it chooses.
Zhang, Yu-Zhong, Li, Song-Song, Chen, Bo
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Dynamic load balancing of parallel road traffic simulation [PDF]

open access: yes, 2010
The objective of this research was to investigate, develop and evaluate dynamic load-balancing strategies for parallel execution of microscopic road traffic simulations.
Igbe, D.
core   +1 more source

Quantitative Analysis of Balancing Range for Single-Phase 3L-NPC Converters

open access: yesEnergies
Multiple techniques have been suggested to achieve control balance in single-phase three-level neutral-point clamped (3L-NPC) converters. Nevertheless, there is a deficiency of quantitative calculations related to the extent of balancing.
Ziying Wang   +5 more
doaj   +1 more source

Phase Balancing Home Energy Management System Using Model Predictive Control

open access: yesEnergies, 2018
Most typical distribution networks are unbalanced due to unequal loading on each of the three phases and untransposed lines. In this paper, models and methods which can handle three-phase unbalanced scenarios are developed.
Bharath Varsh Rao   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Heuristic methods for cost-oriented assembly line balancing: a survey [PDF]

open access: yes
This paper is concerned with cost-oriented assembly line balancing. This problem occurs especially in the final assembly of automotives, consumer durables or personal computers, where production is still very labour- intensive, and where the wage rates ...
Matthias Amen
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

AN EMPIRICAL INVESTIGATION ON THE SUSTAINABILITY OF BALANCING ITEM OF BALANCE OF PAYMENT ACCOUNTS FOR OIC MEMBER COUNTRIES [PDF]

open access: yes
This study aims to examine the sustainability of balancing item (???net errors and omissions') of balance of payment accounts for OIC (Organisation of the Islamic Conference) member countries.
Tuck Cheong Tang, Evan Lau
core  

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