Results 121 to 130 of about 21,065,471 (291)

Synchronous Measurement Method of Two-phase Flow Phase Field and Concentration Field Based on Wire-mesh Sensor

Yuanzineng kexue jishu
It is crucial to understand the internal mixing behavior accurately of the fuel assemblies in the nuclear reactor which could optimize design and safety analysis.
XIA Xinyu1, 2, YAN Xu2, 3, FU Junsen2, 3, XIAO Yao1, 2, 3, , GU Hanyang2, 3
doaj   +1 more source

Phase-field Modeling of Irradiation Effect on Microstructural Evolution in Mo-Re Alloy during Low-temperature Aging

Yuanzineng kexue jishu
Irradiation damage of fuel cladding materials is the critical bottleneck limiting the safe, long-term operation of advanced high-temperature nuclear reactors.
LAN Xun1, SUN Dan1, LONG Ziyao1, NI Xue2, CAI Shunyi2, LI Yuanming1, JIAO Yongjun1, QIU Xi1, , LU Yong2,
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Study on the two-phase flow behavior in batch transportation of liquid ammonia and product oil

You-qi chuyun
Objective Batch transportation of liquid ammonia via product oil pipelines can expand transportation routes, reduce costs, and enhance pipeline efficiency to address the low throughput of existing product oil pipelines.
Xin HUANG, Hongxiang SHI, Yilong LI, Weidong LI, Pengbo YIN, Zhenchao LI, Lin TENG, Lilong JIANG   +7 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Numerical simulation of electrohydrodynamics of a compound drop based on the ternary phase field method. [PDF]

Sci Prog, 2020
Su Y, Yu T, Wang G, Zhang C, Liu Z.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Editorial: Phase field method and integrated computing materials engineering

Frontiers in Materials, 2023
Yu-Hong Zhao, Yu-Hong Zhao
doaj   +1 more source

Mechanism of fracture expansion in deep shale by supercritical CO2 fracturing

Meitan xuebao
Deep shale reservoirs are subjected to high-temperature and high-stress conditions, under which the mechanical properties of shale gradually transform from elastic-brittle to ductile-plastic behavior, making it difficult to form complex fracture networks.
Xiang AO, Liangfeng LAI, Zhaohui LU, Hongkun TANG, Zuping XIANG   +4 more
doaj   +1 more source

Additive Manufacturing of Cementitious Materials by Selective Paste Intrusion: Numerical Modeling of the Flow Using a 2D Axisymmetric Phase Field Method. [PDF]

Materials (Basel), 2020
Pierre A, Weger D, Perrot A, Lowke D.
europepmc   +1 more source