Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Multi-phase System Supplied by SVM VSI: A New Fast Algorithm to Compute Duty Cycles [PDF]
La version éditeur de cette article est disponible à l'adresse suivante : http://www.epe-association.org/epe/index.phpMany authors proposed SVM VSI applied to multi-phase ...
HAUTIER, Jean-Paul +2 more
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
High resolution digital holographic synthetic aperture applied to deformation measurement and extended depth of field method [PDF]
This paper discusses the potential of the synthetic-aperture method in digital holography to increase the resolution, to perform high accuracy deformation measurement, and to obtain a three-dimensional topology map.
Claus, Daniel
core +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The effect of forest dislocations on the evolution of a phase-field model for plastic slip [PDF]
We consider the gradient flow evolution of a phase-field model for crystal dislocations in a single slip system in the presence of forest dislocations.
Kurzke, Matthias W. +3 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Using Phase-Field Modeling With Adaptive Mesh Refinement To Study Elasto-Plastic Effects In Phase Transformations [PDF]
This thesis details work done in the development of the phase field model which allows simulation of elasticity with diffuse interfaces and the extension of a thin interface analysis developed by previous authors to study non-dilute ideal alloys ...
Greenwood, Michael
core
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Athermal resistance to phase interface motion due to precipitates: A phase field study [PDF]
Athermal resistance to the motion of a phase interface due to a precipitate is investigated. The coupled phase field and elasticity equations are solved for the phase transformation (PT).
Levitas, Valery, Javanbakht, Mahdi
core

