Results 121 to 130 of about 21,028,603 (293)

Synchronous Measurement Method of Two-phase Flow Phase Field and Concentration Field Based on Wire-mesh Sensor

Yuanzineng kexue jishu
It is crucial to understand the internal mixing behavior accurately of the fuel assemblies in the nuclear reactor which could optimize design and safety analysis.
XIA Xinyu1, 2, YAN Xu2, 3, FU Junsen2, 3, XIAO Yao1, 2, 3, , GU Hanyang2, 3
doaj   +1 more source

Phase-field Modeling of Irradiation Effect on Microstructural Evolution in Mo-Re Alloy during Low-temperature Aging

Yuanzineng kexue jishu
Irradiation damage of fuel cladding materials is the critical bottleneck limiting the safe, long-term operation of advanced high-temperature nuclear reactors.
LAN Xun1, SUN Dan1, LONG Ziyao1, NI Xue2, CAI Shunyi2, LI Yuanming1, JIAO Yongjun1, QIU Xi1, , LU Yong2,
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Study on the two-phase flow behavior in batch transportation of liquid ammonia and product oil

You-qi chuyun
Objective Batch transportation of liquid ammonia via product oil pipelines can expand transportation routes, reduce costs, and enhance pipeline efficiency to address the low throughput of existing product oil pipelines.
Xin HUANG, Hongxiang SHI, Yilong LI, Weidong LI, Pengbo YIN, Zhenchao LI, Lin TENG, Lilong JIANG   +7 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Numerical simulation of electrohydrodynamics of a compound drop based on the ternary phase field method. [PDF]

Sci Prog, 2020
Su Y, Yu T, Wang G, Zhang C, Liu Z.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Editorial: Phase field method and integrated computing materials engineering

Frontiers in Materials, 2023
Yu-Hong Zhao, Yu-Hong Zhao
doaj   +1 more source

Mechanism of fracture expansion in deep shale by supercritical CO2 fracturing

Meitan xuebao
Deep shale reservoirs are subjected to high-temperature and high-stress conditions, under which the mechanical properties of shale gradually transform from elastic-brittle to ductile-plastic behavior, making it difficult to form complex fracture networks.
Xiang AO, Liangfeng LAI, Zhaohui LU, Hongkun TANG, Zuping XIANG   +4 more
doaj   +1 more source

Additive Manufacturing of Cementitious Materials by Selective Paste Intrusion: Numerical Modeling of the Flow Using a 2D Axisymmetric Phase Field Method. [PDF]

Materials (Basel), 2020
Pierre A, Weger D, Perrot A, Lowke D.
europepmc   +1 more source