Results 81 to 90 of about 2,093,108 (313)
Effect of Number of Variants of Zirconium Hydride on Grain Growth of Zirconium
Metals, 2020 The microstructure characteristics of Zr-hydride in Zr are important concerns in metallurgy and nuclear engineering. In particular, it is known that the correlation between hydride and the grain boundary microstructure has a great influence on properties.
Bohyun Yoon, Kunok Chang
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Modeling and computation of two phase geometric biomembranes using surface finite elements [PDF]
, 2010 Biomembranes consisting of multiple lipids may involve phase separation phenomena leading to coexisting domains of different lipid compositions.
Stinner, Björn, Elliott, Charles M.
core +1 more source
Phase field simulations on topological ferroelectric domains in nanoscale antidot arrays
Journal of Advanced DielectricsFerroelectric topological nanostructures have attracted great attention over the past decade. In this work, the ferroelectric domain structures in nanoscale antidot structures are explored using the phase-field method.
Yixi Huang, Jiong Wang, Pingping Wu
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.We present extensive testing in order to find the optimum balance among errors associated with time integration, spatial discretization, and splitting for a
Bansel, Gurvinder Singh
core
Flux Weakening Strategy Optimization for Five-Phase PM Machine with Concentrated Windings [PDF]
, 2012 The paper applies an Efficient Global Optimization method (EGO) to improve the efficiency, in flux weakening region, of a given 5-phase Permanent Magnet (PM) machine. An optimal control for the four independent currents is thus defined.
JILIN, Gong +3 more
core
A 3D lattice Boltzmann – phase-field model of three-phase contact line dynamics on curved boundaries
Applied and Computational MechanicsIn this paper, we present a three-dimensional multiphase fluid lattice Boltzmann model based on the phase-field theory. The conservative Allen-Cahn equation was used to describe the interface dynamics between two different fluids.
Benioug M.
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source