Results 111 to 120 of about 967,094 (265)

Topology Optimization for Microfluidic Mixers by a Phase Field Method

open access: yesInternational Journal for Numerical Methods in Fluids
ABSTRACT We investigate multi‐physical topology optimization for microfluidic mixers. Starting from the Ising model, we derive a thermodynamically consistent Ginzburg–Landau free energy functional that incorporates the objective functional as an effective external field, providing a physically interpretable framework for phase‐field ...
Liu, Zongyuan   +2 more
openaire   +2 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Synchronous Measurement Method of Two-phase Flow Phase Field and Concentration Field Based on Wire-mesh Sensor

open access: yesYuanzineng kexue jishu
It is crucial to understand the internal mixing behavior accurately of the fuel assemblies in the nuclear reactor which could optimize design and safety analysis.
XIA Xinyu1, 2, YAN Xu2, 3, FU Junsen2, 3, XIAO Yao1, 2, 3, , GU Hanyang2, 3
doaj   +1 more source

Study on the two-phase flow behavior in batch transportation of liquid ammonia and product oil

open access: yesYou-qi chuyun
Objective Batch transportation of liquid ammonia via product oil pipelines can expand transportation routes, reduce costs, and enhance pipeline efficiency to address the low throughput of existing product oil pipelines.
Xin HUANG   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Mechanism of fracture expansion in deep shale by supercritical CO2 fracturing

open access: yesMeitan xuebao
Deep shale reservoirs are subjected to high-temperature and high-stress conditions, under which the mechanical properties of shale gradually transform from elastic-brittle to ductile-plastic behavior, making it difficult to form complex fracture networks.
Xiang AO   +4 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Editorial: Phase field method and integrated computing materials engineering

open access: yesFrontiers in Materials, 2023
Yu-Hong Zhao, Yu-Hong Zhao
doaj   +1 more source

Home - About - Disclaimer - Privacy