Results 61 to 70 of about 1,322,830 (294)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Growth behavior and reliability of interfacial IMC for Sn58Bi/Cu and Sn58Bi–AlN/Cu solder joints applied in IGBT modules

open access: yesJournal of Materials Research and Technology, 2022
The IMC (interfacial intermetallic compound) produced by the metallurgical reaction between the solder and the Cu plate enables the packaging of IGBT (insulated gate bipolar transistor) modules. In this paper, the growth behavior of IMCs of Sn58Bi/Cu and
Xi Wang   +7 more
doaj   +1 more source

Monte Carlo study of dynamic phase transition in Ising metamagnet driven by oscillating magnetic field

open access: yes, 2011
The dynamical responses of Ising metamagnet (layered antiferromagnet) in the presence of a sinusoidally oscillating magnetic field are studied by Monte Carlo simulation.
Acharyya, Muktish
core   +1 more source

Phase-field simulation study of the migration of recrystallization boundaries [PDF]

open access: yesPhysical Review B, 2013
We present simulation results based on a phase-field model that describes the local migration of recrystallization boundaries into varying deformation energy fields. An important finding from the simulations is that the overall migration rate of the recrystallization front can be considerably affected by the variations in the deformed microstructure ...
Moelans, Nele   +3 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Adaptive phase field simulation of quasi-static crack propagation in rocks

open access: yesUnderground Space, 2018
In this study, we present an adaptive phase field method (APFM) for modeling quasi-static crack propagation in rocks. Crack initiation due to positive strains is considered, and a numerical simulation is implemented using a commercial software, COMSOL ...
Shuwei Zhou, Xiaoying Zhuang
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

A multigrid solver for phase field simulation of microstructure evolution [PDF]

open access: yesMathematics and Computers in Simulation, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Liesbeth Vanherpe   +3 more
openaire   +3 more sources

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Investigating the Switching Dynamics of Antiferroelectric Capacitor Using Multidomain Phase-Field Approach

open access: yesIEEE Journal of the Electron Devices Society
Here, we present a compact model based on multidomain phase-field approach that can capture the hysteresis loop and the transient negative capacitance (NC) regions in Metal-Antiferroelectric-Metal structures.
Muhammad Mainul Islam   +5 more
doaj   +1 more source

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