Results 71 to 80 of about 13,291,552 (284)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Adaptive phase field simulation of quasi-static crack propagation in rocks

Underground Space, 2018
In this study, we present an adaptive phase field method (APFM) for modeling quasi-static crack propagation in rocks. Crack initiation due to positive strains is considered, and a numerical simulation is implemented using a commercial software, COMSOL ...
Shuwei Zhou, Xiaoying Zhuang
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Phase‐Field Simulations at the Atomic Scale in Comparison to Molecular Dynamics [PDF]

The Scientific World Journal, 2013
Early solidification is investigated using two different simulation techniques: the molecular dynamics (MD) and the phase‐field (PF) methods. While the first describes the evolution of a system on the basis of motion equations of particles, the second grounds on the evolution of continuous local order parameter field.
Marco Berghoff, Michael Selzer, Britta Nestler   +2 more
openaire   +5 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

ToPoliNano: Nano-magnet Logic Circuits Design and Simulation [PDF]

, 2013
Among the emerging technologies Field-Coupled devices like Quantum dot Cellular Automata are particularly interesting. Of all the practical implementations of this principle NanoMagnet Logic shows many important features, such as a very low power ...
Graziano, Mariagrazia, Zamboni, Maurizio, Vacca, Marco, Frache, Stefano   +3 more
core  

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Intrinsic, multiplexable sensors for electric field strength using structural slow light in phase-shifted fibre Bragg gratings [PDF]

, 2012
In this paper we demonstrate through simulation the potential for phase-shifted fibre Bragg gratings incorporating structural slow light to enable intrinsic reflection-mode point sensors for electric field or voltage.
Niewczas, Pawel, Orr, Philip
core   +4 more sources

Propagation law of hydraulic-induced fractures in directional hydraulic fracturing with prefabricated cracks based on phase-field method

Yantu gongcheng xuebao
To investigate the propagation and evolution laws of induced cracks in rocks under directional hydraulic fracturing, a phase-field model is developed.
LIANG Xin 1, 2 , HOU Peng 3 , XUE Yi 1, 2, LIU Jia 1, 2, GAO Feng 4
doaj   +1 more source