Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2013 ElsevierThis paper reports on a validation study of CFD models used to predict the effect of PCM clay boards on the ...
Gowreesunker, BL, Tassou, SA
core +1 more source
To investigate the propagation and evolution laws of induced cracks in rocks under directional hydraulic fracturing, a phase-field model is developed.
LIANG Xin 1, 2 , HOU Peng 3 , XUE Yi 1, 2, LIU Jia 1, 2, GAO Feng 4
doaj +1 more source
Comparative analysis of different numerical schemes in solute trapping simulations by using the phase-field model with finite interface dissipation [PDF]
Two different numerical schemes, the standard explicit scheme and the time-elimination relaxation one, in the framework of phase-field model with finite interface dissipation were employed to investigate the solute trapping effect in a Si-4.5 at.
Yang X. +5 more
doaj +1 more source
Phase‐Field Simulations at the Atomic Scale in Comparison to Molecular Dynamics [PDF]
Early solidification is investigated using two different simulation techniques: the molecular dynamics (MD) and the phase‐field (PF) methods. While the first describes the evolution of a system on the basis of motion equations of particles, the second grounds on the evolution of continuous local order parameter field.
Marco Berghoff +2 more
openaire +5 more sources
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Using Phase-Field Modeling With Adaptive Mesh Refinement To Study Elasto-Plastic Effects In Phase Transformations [PDF]
This thesis details work done in the development of the phase field model which allows simulation of elasticity with diffuse interfaces and the extension of a thin interface analysis developed by previous authors to study non-dilute ideal alloys ...
Greenwood, Michael
core
Impact of PWM strategies on RMS current of the DC-link Voltage Capacitor of a dual-three phase drive [PDF]
The major drawback of usual dual three-phase AC machines, when supplied by a Voltage Source Inverter (VSI), is the occurrence of extra harmonic currents which circulate in the stator windings causing additional losses and constraints on the power ...
ROUHANA, Najib +5 more
core +1 more source
Phase-field simulation of solidification dendritic segregation in Ti-45Al alloy [PDF]
The microstructures and mechanical properties of TiAl alloys are directly linked to micro-segregation which cannot be avoided during solidification.
Yu-tuo Zhang , Yun Chi, Chun-qing Hu
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source

