Results 111 to 120 of about 941,423 (318)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2003 If remembering is discriminative behaviour along the dimension of time and if, as Sargisson and White (2001) argued, generalisation around a peak can occur in this behaviour, then the peak shift which has been shown in discrimination along so many other ...
Hoan, Andros
core
Chemical Control of Peptide Material Phase Transitions
, 2020 Progressive solute-rich polymer phase transitions provide pathways for achieving ordered supramolecular assemblies. Intrinsically disordered protein domains specifically regulate information in biological networks via conformational ordering.
Ming-Chien, Hsieh +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Changes in Columbus Operations and Outlook to Long-term Operation Phase
, 2011 Since the activation of Columbus on 12 February 2008 three years of busy and partly challenging operation have been performed by the Columbus FCT. The last year was mainly driven by the ground segment schedule to update the control rooms and servers to
Sabath, Dieter +2 more
core
Phase-Shift High-Speed Valve for Switch-Mode Control
, 2010 Hydraulic applications requiring a variation in the speed or torque of actuators have historically used throttling valve control or a variable displacement pump or motor.
James D. Van de Ven, Allan Katz
core +1 more source
A Summary of Bidirectional DC-DC Converter Applied in Power Electronic Transformer
Kongzhi Yu Xinxi Jishu, 2017 As an intermediate link of power electronic transformer(PET), bidirectional DC-DC converter plays an important role in electrical isolation and electrical conversion. In this paper, the development of PET in recent years was illustrated.
WANG Yang +4 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2017 Hao Guo,1 Ziming Wang,1 Quanyin Du,1 Pan Li,2 Zhigang Wang,2 Aimin Wang1 1Department of Orthopedics, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China; 2Chongqing Key Laboratory of Ultrasound Molecular ...
Du Q, Wang A, Guo H, Li P, Wang Z
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Phase-Shift Interleaving Control of Variable-Phase Switched-Capacitor Converters
IEEE Transactions on Industrial Electronics, 2013 This paper proposes a phase-shift interleaving control method for variable-phase switched-capacitor (SC) converters that can perform voltage conversions with little electromagnetic interference over a wide range of operating condition. This is achieved by having multiple units of SC converter connected in parallel and an N-state hysteresis unit ...
Sitthisak Kiratipongvoot +2 more
openaire +3 more sources