Results 111 to 120 of about 940,971 (329)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Steering the propagation of finite-energy Airy beam by spatial phase modulation

Results in Physics, 2019
The effect of spatial phase modulation on the propagation of finite-energy Airy beam (FEAB) is investigated. A sinusoidal phase is introduced on a FEAB and the propagation behavior is analyzed in Kerr medium by numerical simulation.
Peng Chen, Hongcheng Wang, Lifu Zhang, Ye Liu, Dongxiong Ling   +4 more
doaj   +1 more source

Superfast multifrequency phase-shifting technique with optimal pulse width modulation

Optics Express, 2011
The technique of generating sinusoidal fringe patterns by defocusing squared binary structured ones has numerous merits for high-speed three-dimensional (3D) shape measurement. However, it is challenging for this method to realize a multifrequency phase-shifting (MFPS) algorithm because it is difficult to simultaneously generate high-quality sinusoidal
Wang, Yajun, Zhang, Song
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Direct quadrature phase shift keying modulator using six-port technology

Electronics Letters, 2005
A direct quadrature phase shift keying modulator based on six-port technology is presented. The modulator comprises a six-port circuit, a switch matrix and open and short terminations. Using this modulator, direct phase shift keying modulation was achieved.
Y. Zhao, C. Viereck, J.F. Frigon, R.G. Bosisio, K. Wu   +4 more
openaire   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Programmable rate modem utilizing digital signal processing techniques [PDF]

The need for a Programmable Rate Digital Satellite Modem capable of supporting both burst and continuous transmission modes with either Binary Phase Shift Keying (BPSK) or Quadrature Phase Shift Keying (QPSK) modulation is discussed.
Naveh, Arad
core   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

The All-fiber MZI Structure for Optical DPSK Demodulation and Optical PSBT Encoding [PDF]

Journal of Systemics, Cybernetics and Informatics, 2006
Since the beginning of optical telecommunications, the most simple modulation format has been employed in optical links. This format is called OOK (On Off Keying).
Guillaume Ducournau, Olivier Latry, Mohamed Ketata   +2 more
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source