Results 41 to 50 of about 504,913 (304)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

A Novel Digital Modulation Recognition Algorithm Based on Deep Convolutional Neural Network

Applied Sciences, 2020
The modulation recognition of digital signals under non-cooperative conditions is one of the important research contents here. With the rapid development of artificial intelligence technology, deep learning theory is also increasingly being applied to ...
Kaiyuan Jiang, Jiawei Zhang, Haibin Wu, Aili Wang, Yuji Iwahori   +4 more
doaj   +1 more source

Nonreciprocal phase shifts in spatiotemporally modulated systems

Physical Review B
Materials and devices subject to spatiotemporal modulation of their effective properties have a demonstrated ability to support nonreciprocal transmission of waves. Most notably, spatiotemporally modulated systems can restrict wave transmission to only one direction; i.e.
Jiuda Wu, Behrooz Yousefzadeh
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Benefits and Limits of Modulation Formats for Optical Communications

Advances in Electrical and Electronic Engineering, 2014
This paper is focused on benefits and limits of intensity and phase modulation formats used in optical communications. The simulation results are obtained using OptSim software environment, employing Time Domain Split Step method.
Rajdi Agalliu, Michal Lucki
doaj   +1 more source

25 Gbit/s differential phase-shift-keying signal generation using directly modulated quantum-dot semiconductor optical amplifiers [PDF]

, 2015
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Appl. Phys. Lett. 106, 213501 (2015) and may be found at https://doi.org/10.1063/1.4921785.Error-free
Bimberg, Dieter, Bunge, C.-A., Meuer, C., Schmeckebier, Holger, Schubert, C., Stubenrauch, M., Zeghuzi, A.   +6 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Hybrid modulation strategy for minimizing backflow power under dual phase shift modulation

Energy Reports
The dual active bridge (DAB) converter is essential for direct current (DC) microgrids, providing galvanic isolation, high power density, and bidirectional power transfer.
Xiaoqian Yue, Fei Yu, Jiaming Qi, Haoyang Xue, Xinrui Pei   +4 more
doaj   +1 more source