Results 71 to 80 of about 287,761 (311)
Simulating Coxian phase‐type distributions for patient survival [PDF]
AbstractCoxian phase‐type distributions are a special type of Markov model that can be used to represent survival times in terms of phases through which an individual may progress until they eventually leave the system completely. Previous research has considered the Coxian phase‐type distribution to be ideal in representing patient survival in ...
Marshall, A, ZENGA, MARIANGELA
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Wavefront Aberration Sensor Based on a Multichannel Diffractive Optical Element
We propose a new type of a wavefront aberration sensor, that is, a Zernike matched multichannel diffractive optical filter, which performs consistent filtering of phase distributions corresponding to Zernike polynomials. The sensitivity of the new sensor
Svetlana N. Khonina +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Performance Evaluation of Controlled Arrival Rate System through Matrix Geometric Method Using Transient Analysis [PDF]
Performance evaluation based on transient analysis has significant importance to those systems which never reached at equilibrium. In this paper, we develop and analyze the system through controlled arrival rate using internal limits.
Wajiha Shah +2 more
doaj
A Parameter Estimation Method of Shock Model Constructed with Phase-Type Distribution on the Condition of Interval Data [PDF]
Long Wang, Yue Li, Yanling Qian, Xu Luo
openalex +1 more source
Phase Distribution Properties of a Moving Five-Level (Inverted Y)-Type Atom in the Presence of a Non-linear Medium [PDF]
Sameh T. Korashy +2 more
openalex +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

