Results 91 to 100 of about 1,017,313 (318)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Dans cet exposé, je compte discuter deux cas en physique où une relation de composition inhabituelle semble à l’œuvre : les transitions de phase proches de la valeur critique et l’effet Hall quantique fractionnaire.
Métaphysique de la composition +1 more
core
Optical phase curves as diagnostics for aerosol composition in exoplanetary atmospheres [PDF]
Optical phase curves have become one of the common probes of exoplanetary atmospheres, but the information they encode has not been fully elucidated. Building on a diverse body of work, we upgrade the Flexible Modelling System to include scattering in ...
Oreshenko, Maria +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The effect of coating condition and aqueous phase composition on the performance of thin film composite reverse osmosis flat sheet membranes [PDF]
Thin film composite (TFC) layers are formed using interfacial polymerization reaction between an aqueous phase and organic phase on membrane supports. In the preparation of thin film composite membrane, there are many interfacial reaction factors that ...
Kormin, Faridah
core
Composition-tuned smeared phase transitions
Phase transitions in random systems are smeared if individual spatial regions can order independently of the bulk system. In this paper, we study such smeared phase transitions (both classical and quantum) in substitutional alloys A 1-xB x that can be ...
Fawaz Hrahsheh +5 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Chalcogenide compounds are the main characters in a revolution in electronic memories. These materials are used to produce ultrafast ovonic threshold switches (OTSs) with good selectivity and moderate leakage current and phase-change memories (PCMs) with
Vijay K. Narasimhan (1477432) +7 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

