Results 141 to 150 of about 26,153,681 (361)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Application of predictive control to a three-phase NPC converter: from simulation to a real platform [PDF]

open access: yes, 2012
This final degree thesis is concerned with the application of the Predictive Control with Multilevel Converters, specifically the application of the Finite Set Model Predictive Control (FS-MPC) in a Three-Level Neutral Point Clamped (3L-NPC) Inverter.
Bassan, Nicola
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Pedestrian Control at Intersections: Phase IV

open access: yes, 2000
This report represents a real-time system for pedestrian tracking in sequences of greyscale images acquired by a stationary camera. Researchers also developed techniques for recognizing pedestrians' actions, such as running and walking, and ...
Papanikolopoulos, Nikolaos P.   +1 more
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Pedestrian Control at Intersections (Phase I)

open access: yes, 1996
This report describes a real-time system for tracking pedestrians in sequences of grayscale images acquired by a stationary camera. The system outputs the spatio-temporal coordinates of each pedestrian during the period when the pedestrian is visible ...
Richards, Charles A.   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Series Compensated Low Frequency Transformers Emulating Multipulse Rectifiers for Harmonic Current Content Minimization in Electrical Grids

open access: yesIEEE Access
This paper explores the use of series compensated low frequency transformers (SCLFT), operating in parallel to traditional low frequency transformers (LFT), to attenuate harmonic distortion caused by nonlinear loads in electrical networks.
Carlos A. Munoz   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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