Results 161 to 170 of about 26,026,661 (311)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Colloidal Phase Control in Plasmonic Metal Oxide Nanocrystals via Competitive Metal-Ligand Equilibria. [PDF]

Angew Chem Int Ed Engl
Kang J, Qian D, Lee J, Conrad DL, Oberlander JD, Berry MW, Liu J, Anslyn EV, Truskett TM, Milliron DJ.   +9 more
europepmc   +1 more source

Electrical Phase Control Based on Graphene Surface Plasmon Polaritons in Mid-infrared. [PDF]

Nanomaterials (Basel), 2020
Wang Y, Liu H, Wang S, Cai M, Zhang H, Qiao Y.   +5 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Double-layer silicon-based optical phased array transceiver based on cascaded phase control. [PDF]

Sci Rep
Zhang Y, Wang R, Wei M, Jiang R, Zhang H, Huang JS.   +5 more
europepmc   +1 more source

Phase Control Pattern and Phase Regulating Performance of a Thyristor-Controlled Phase Shifter

IEEJ Transactions on Power and Energy, 2000
Noriyuki Uchiyama, Masahiro Watanabe, Naoki Kasahara, Hiroshi Arita   +3 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Carrier-Envelope Phase Control in Terahertz Pulse Generation Using InAs Ribbon Metasurfaces. [PDF]

ACS Photonics
Norman S, Jung H, Seddon J, Prescott S, Harris CT, Addamane S, Brener I, Mitrofanov O.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Laser-Induced Phase Control of Morphotropic Phase Boundary Hafnium-Zirconium Oxide. [PDF]

ACS Appl Mater Interfaces
Kim SM, Kim M, Lee CB, Choi U, Kwon MG, Kim KS, Kim J, Hwang HJ, Lee BH.   +8 more
europepmc   +1 more source