Results 121 to 130 of about 4,298,588 (299)

A General Method for Drawing Area-Proportional Euler Diagrams [PDF]

open access: yes, 2011
Area-proportional Euler diagrams have many applications, for example they are often used for visualizing data in medical and biological domains. There have been a number of recent research efforts to automatically draw Euler diagrams when the areas of ...
Howse, John   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The Impact of Shape on the Perception of Euler Diagrams [PDF]

open access: yes, 2014
Euler diagrams are often used for visualizing data collected into sets. However, there is a significant lack of guidance regarding graphical choices for Euler diagram layout.
Howse, John   +10 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Evaluating the Comprehension of Euler Diagrams [PDF]

open access: yes, 2005
We describe an empirical investigation into layout criteria that can help with the comprehension of Euler diagrams. Our work is intended to inform automatic Euler diagram layout research by confirming the importance of various Euler diagram aesthetic ...
Benoy, Florence, Rodgers, Peter
core  

Tangential azeotropy in binary constituents of ternary azeotropic mixtures.

open access: yesТонкие химические технологии, 2009
Transformations of phase diagrams of vapor-liquid equilibrium for ternary systems containing single triple azeotrope are considered. The considered transformations include the stage of border tangential azeotropy.
L. A. Serafimov   +2 more
doaj  

Two-Phase Equilibrium Properties in Charged Topological Dilaton AdS Black Holes

open access: yesAdvances in High Energy Physics, 2016
We discuss phase transition of the charged topological dilaton AdS black holes by Maxwell equal area law. The two phases involved in the phase transition could coexist and we depict the coexistence region in P-v diagrams. The two-phase equilibrium curves
Hui-Hua Zhao, Li-Chun Zhang, Ren Zhao
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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