Results 91 to 100 of about 424,619 (265)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Current derivative measurement using closed-loop hall-effect current sensor
The Journal of Engineering, 2019 This paper discusses a method of the current derivative measurement using a standard closed-loop Hall-effect current sensor. The proposed method can operate with PWM-driven inverters and provides the estimation of motor-phase inductances required for an ...
A. Anuchin +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Polynomial phase estimation by phase unwrapping
, 2012 Estimating the coefficients of a noisy polynomial phase signal is important in fields including radar, biology and radio communications. One approach attempts to perform polynomial regression on the phase of the signal. This is complicated by the fact that the phase is wrapped modulo 2πand must be unwrapped before regression can be performed.
McKilliam, Robby G. +4 more
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Simplified Second-Order Generalized Integrator - Frequency-Locked Loop
Advances in Electrical and Electronic Engineering, 2019 Second-Order Generalized Integrator -- Frequency-Locked Loop (SOGI-FLL) is a popular technique available in the grid synchronization literature. This technique uses gain normalization in the frequency locked-loop.
Hafiz Ahmed, Mohamed Benbouzid
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Iterative phase estimation [PDF]
Journal of Physics A: Mathematical and Theoretical, 2009 We give an iterative algorithm for phase estimation of a parameter theta, which is within a logarithmic factor of the Heisenberg limit. Unlike other methods, we do not need any entanglement or an extra rotation gate which can perform arbitrary rotations with almost perfect accuracy: only a single copy of the unitary channel and basic measurements are ...
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source