Results 121 to 130 of about 21,073,531 (290)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Numerical simulation of electrohydrodynamics of a compound drop based on the ternary phase field method. [PDF]
Sci Prog, 2020 Su Y, Yu T, Wang G, Zhang C, Liu Z.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Vietnam Journal of MechanicsThis paper focuses on studying the effect of the interface between the mortar matrix and aggregate particles on the meso-scale behavior of steel fiber-reinforced concrete (SFRC). To achieve this, a phase field model enhanced by a cohesive law is applied
Hoang-Quan Nguyen +3 more
doaj +1 more source
Additive Manufacturing of Cementitious Materials by Selective Paste Intrusion: Numerical Modeling of the Flow Using a 2D Axisymmetric Phase Field Method. [PDF]
Materials (Basel), 2020 Pierre A, Weger D, Perrot A, Lowke D.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Youqicang pingjia yu kaifaImbibition plays a crucial role in waterflood development and the soaking stage after fracturing in tight oil reservoirs, serving as an effective method to enhance oil recovery.
QI HUAIYAN +5 more
doaj
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Phase-field modelling of fatigue crack propagation
, 2023 Fracture prediction and modeling are crucial in studying the behavior of materials under stress. This research focuses on utilizing the phase field method for accurate fracture prediction, which offers distinct advantages over traditional methods by ...
Purantagi, Ankeet Mohan +4 more
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