Results 101 to 110 of about 1,024,086 (309)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Thermodynamically-consistent derivation and computation of twinning and fracture in brittle materials by means of phase-field approaches in the finite element method

, 2022
A theoretical-computational framework is proposed for predicting the failure behavior of two anisotropic brittle materials, namely, single crystal magnesium and boron carbide.
Jafarzadeh, Hossein, Abali, Bilen Emek, Hogan, James D., Amirian, Benhour, Reali, Alessandro   +4 more
core   +1 more source

Progress in phase field research of dead lithium in lithium batteries

工程科学学报
In recent years, the increase in people’s demand for energy has led to the development of secondary batteries. Because of its high theoretical capacity and low electrochemical potential, lithium metal has gradually become the preferred negative electrode
Jing LIU, Huiyi CHEN, Huiyu LIU, Shu LI
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finite element method for conserved phase field models Solid state phase transformations

, 2010
Cahn-Hilliard type of phase field model coupled with elasticity equations is used to derive governing equations for the stress-mediated diffusion and solid state phase transformations. The partial differential equations governing diffusion and mechanical
Zaeem, Mohsen
core   +1 more source

Demodulation of Spatial Carrier Images: Performance Analysis of Several Algorithms Using a Single Image [PDF]

, 2013
http://link.springer.com/article/10.1007%2Fs11340-013-9741-6#Optical full-field techniques have a great importance in modern experimental mechanics.
Esquis, P., Dupré, J.C., VALLE, Valéry, ROTINAT, René, PICART, Pascal, BORNERT, Michel, BADULESCU, Claudiu, DUPRE, Jean Christophe, EQUIS, Sébastien, GREDIAC, Michel, MOLIMARD, Jerome   +10 more
core   +1 more source

Modelling of Fatigue Microfracture in Porous Sintered Steel Using a Phase-Field Method. [PDF]

Materials (Basel), 2023
Tomić Z, Jarak T, Lesičar T, Gubeljak N, Tonković Z.   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Numerical Analysis of Droplet Impacting on an Immiscible Liquid via Three-Phase Field Method. [PDF]

Micromachines (Basel), 2023
Hu Q, Hu F, Xu D, Zhang K.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source