Results 81 to 90 of about 1,024,086 (309)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Z(_N)-symmetric field theories and the thermodynamic Bethe ansatz [PDF]

, 1996
This thesis is concerned with perturbed conformal field theory, the thermodynamic Bethe ansatz technique and applications to statistical mechanics. In particular, the phase space of two dimensional Z(_N)-symmetric statistical models is examined using ...
Thompson, K.E., Thompson, Kevin Edward
core  

Phase-field modelling of fatigue crack propagation

, 2023
Fracture prediction and modeling are crucial in studying the behavior of materials under stress. This research focuses on utilizing the phase field method for accurate fracture prediction, which offers distinct advantages over traditional methods by ...
Purantagi, Ankeet Mohan, Zetterlund, Gustav, Degwekar, Sharvil, Tzanetou, Afroditi, Åkesson, Louise   +4 more
core  

A modified damage and fracture phase field model considering heterogeneity for rock‐like materials

Deep Underground Science and Engineering, 2023
Damage and fracture are the most extensive failure modes of rock materials, which may easily induce disaster and instability of engineering structures.
Xuxin Chen, Zhe Qin
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Flux Weakening Strategy Optimization for Five-Phase PM Machine with Concentrated Windings [PDF]

, 2012
The paper applies an Efficient Global Optimization method (EGO) to improve the efficiency, in flux weakening region, of a given 5-phase Permanent Magnet (PM) machine. An optimal control for the four independent currents is thus defined.
JILIN, Gong, ASLAN, Bassel, SEMAIL, Eric, GILLON, Frédéric   +3 more
core  

Study on Elastoplastic Damage and Crack Propagation Mechanisms in Rock Based on the Phase Field Method

Applied Sciences
To overcome the limitation of traditional elastic phase field models that neglect plastic deformation in rock compressive-shear failure, this study developed an elastoplastic phase field fracture model incorporating plastic strain energy and established ...
Jie Zhang, Guang Qin, Bin Wang
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Phase-field modeling of thermo-mechanical coupled brittle fracture for transversely isotropic rock

Yantu gongcheng xuebao
Thermally induced deformation and fracture of bedding rocks are critical concerns in geotechnical engineering, including geothermal mining and nuclear waste storage, as these phenomena are strongly influenced by material anisotropy.
ZHANG Chengkai 1, 2, ZHOU Shuwei 1, 2, ZHANG Yuheng 1, 2, TIAN Junyao 1, 2, ZHUANG Xiaoying 1, 2
doaj   +1 more source