Results 101 to 110 of about 1,799,934 (343)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Scintillation modeling with random phase gradient screens

Journal of Space Weather and Space Climate
Multiple studies of scintillation phenomena have shown that, in certain situations, the intense phase fluctuations of trans-ionospheric radio signals are associated with the scattering on strong electron density gradients.
Vasylyev Dmytro, Cahuasquí Juan Andrés, Hoque Mainul, Jakowski Norbert, Kriegel Martin, David Paul, Tagargouste Youssef, Buchert Stephan, Berdermann Jens   +8 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Low-complexity implementation of convex optimization-based phase retrieval

, 2018
Phase retrieval has important applications in optical imaging, communications and sensing. Lifting the dimensionality of the problem allows phase retrieval to be approximated as a convex optimization problem in a higher-dimensional space.
Arik, Sercan O., Kahn, Joseph M.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Phase and amplitude gradient waveguide coupled metasurfaces

Scientific Reports
This paper presents a novel silicon-based metasurface-coated one-dimensional (1D) slab waveguide. The proposed idea can easily engineer and mold guided waves into any desired free-space mode and provide the wavefront control of optical metasurfaces, such
Yasaman Tanhayivash, Hadi Soofi, Saeid Nikmehr   +2 more
doaj   +1 more source

A sharp interface model for the propagation of martensitic phase boundaries [PDF]

, 2008
A model for the quasistatic evolution of martensitic phase boundaries is presented. The model is essentially the gradient flow of an energy that can contains elastic energy due to the underlying change in crystal structure in the course of the phase ...
Bhattacharya, Kaushik, Dondl, Patrick W.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Wideband Phase-Gradient Metasurface Antenna With Focused Beams

IEEE Access, 2019
A transmitting lens antenna with focused beams by employing four-layer phase-gradient metasurface (PGMS) is proposed. A wideband slot-coupled antenna is mounted close to the focal position of the PGMS acting as a feed.
Jia-Jun Liang, Guan-Long Huang, Jia-Ning Zhao, Zhi-Jian Gao, Tao Yuan   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source