Results 101 to 110 of about 5,552,824 (295)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Plasmonic phase-gradient metasurface for spontaneous emission control [PDF]
, 2015 We combine the concept of phase-gradient metasurfaces with fluorescence directionality control of an ensemble of incoherent emitters. We design a periodic metasurface to control the scattering amplitude of the lattice in momentum space.
Schokker, A.H. +6 more
core +1 more source
, 2022 Phase-gradient metasurfaces (PGMs) have provided unprecedented opportunities for manipulating light. Here, we reexamine ordinary and well-studied subwavelength metallic gratings (OMGs) from the concept of PGMs to provide more insight into their ...
Jiaqi Quan (12478479) +3 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Wideband Phase-Gradient Metasurface Antenna With Focused Beams
IEEE Access, 2019 A transmitting lens antenna with focused beams by employing four-layer phase-gradient metasurface (PGMS) is proposed. A wideband slot-coupled antenna is mounted close to the focal position of the PGMS acting as a feed.
Jia-Jun Liang +4 more
doaj +1 more source
Correction of gradient-induced phase errors in radial MRI.
, 2014 Purpose To correct gradient-induced phase errors in radial MRI. Methods Gradient-induced eddy currents affect the MRI data acquisition by gradient delays and phase errors that may lead to severe image artifacts for non-Cartesian imaging scenarios such as
Moussavi, A. +11 more
core +1 more source
Gradient estimates for Orlicz double phase problems with variable exponents
, 2022 Baasandorj S, Byun S-S, Lee H-S. Gradient estimates for Orlicz double phase problems with variable exponents. Nonlinear Analysis.
Baasandorj, Sumiya +5 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source