Results 11 to 20 of about 1,964,480 (312)
Phase II metabolism of benzene. [PDF]
Environmental Health Perspectives, 1996 The hepatic metabolism of benzene is thought to be a prerequisite for its bony marrow toxicity. However, the complete pattern of benzene metabolites formed in the liver and their role in bone marrow toxicity are not fully understood. Therefore, benzene metabolism was studied in isolated rodent hepatocytes.
D, Schrenk +6 more
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Phase II monitoring of auto-correlated linear profiles using multivariate linear mixed model [PDF]
International Journal of Industrial Engineering and Production Research, 2021 In the last few decades, profile monitoring in univariate and multivariate environment has drawn a considerable attention in the area of statistical process control.
Rassoul Noorossana, Somayeh Khalili
doaj +1 more source
Malaria Journal, 2018 Background Uganda’s malaria burden includes the sixth highest number of annual deaths in Africa (10,500) with approximately 16 million cases (2013) and the entire population at risk.
Michael Okia +9 more
doaj +1 more source
Nutraceuticals, 2023 Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease showing an exponential increase in its prevalence all over the world. High blood glucose level is one of the main clinical signs of the disease.
Muhammed Majeed +4 more
doaj +1 more source
Randomized Phase II Designs [PDF]
Clinical Cancer Research, 2009 Abstract As the use of molecularly targeted agents, which are anticipated to increase overall survival (OS)and progression-free survival (PFS) but not necessarily tumor response, has increased in oncology, there has been a corresponding increase in the recommendation and use of randomized phase II designs.
Rubinstein, Larry +4 more
openaire +2 more sources
Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility [PDF]
, 2013 Seamless phase II/III clinical trials combine traditional phases II and III into a single trial that is conducted in two stages, with stage 1 used to answer phase II objectives such as treatment selection and stage 2 used for the confirmatory analysis ...
Todd, Susan C. +6 more
core +1 more source
Eight predictive powers with historical and interim data for futility and efficacy analysis
Statistical Theory and Related Fields, 2022 When the historical data of the early phase trial and the interim data of the Phase III trial are available, we should use them to give a more accurate prediction in both futility and efficacy analysis. The predictive power is an important measure of the
Ying-Ying Zhang +2 more
doaj +1 more source
Toxicology Reports, 2015 The present work investigated repeated dose and reproductive toxicity of Calebin A in Wistar rats. A study for assessing the mutagenic potential of Calebin A through an AMES test is also described.
Muhammed Majeed +5 more
doaj +1 more source
Upgrade for Phase II of the Gerda experiment [PDF]
The European Physical Journal C, 2018 The GERDA collaboration is performing a sensitive search for neutrinoless double beta decay of $^{76}$Ge at the INFN Laboratori Nazionali del Gran Sasso, Italy. The upgrade of the GERDA experiment from Phase I to Phase II has been concluded in December 2015.
GERDA Collaboration +114 more
openaire +9 more sources
Aggregate Operators of Neutrosophic Hypersoft Set [PDF]
Neutrosophic Sets and Systems, 2020 Multi-criteria decision making (MCDM) is concerned about organizing and taking care of choice and planning issues including multi-criteria. When attributes are more than one, and further bifurcated, neutrosophic softset environment cannot be used to ...
Muhammad Saqlain +4 more
doaj +1 more source