Results 21 to 30 of about 1,964,480 (312)

A Review on Enhancing Cupriavidus necator Fermentation for Poly(3-hydroxybutyrate) (PHB) Production From Low-Cost Carbon Sources

Frontiers in Bioengineering and Biotechnology, 2022
In the context of a circular economy, bioplastic production using biodegradable materials such as poly(3-hydroxybutyrate) (PHB) has been proposed as a promising solution to fundamentally solve the disposal issue of plastic waste.
Le Zhang, Le Zhang, Zicheng Jiang, To-Hung Tsui, To-Hung Tsui, Kai-Chee Loh, Kai-Chee Loh, Yanjun Dai, Yanjun Dai, Yen Wah Tong, Yen Wah Tong, Yen Wah Tong   +11 more
doaj   +1 more source

Assessment of luteolin isolated from Eclipta alba leaves in animal models of epilepsy

Pharmaceutical Biology, 2017
Context: Eclipta alba (Linn) Hassk. (Asteraceae) has been reported to be a nerve tonic and has been used to treat epilepsy in folk medicine. Objective: The present study isolates and characterizes luteolin from E.
Rufi Tambe, Aditi Patil, Pankaj Jain, Jayant Sancheti, Gauresh Somani, Sadhana Sathaye   +5 more
doaj   +1 more source

Required efficacy for novel therapies in BCG‐unresponsive non‐muscle invasive bladder cancer: Do current recommendations really reflect clinically meaningful outcomes?

Cancer Medicine, 2020
Background Single‐arm trials are currently an accepted study design to investigate the efficacy of novel therapies (NT) in non‐muscle invasive bladder cancer (NMIBC) unresponsive to intravesical Bacillus Calmette‐Guérin (BCG) immunotherapy as randomized ...
Marian S. Wettstein, David Naimark, Thomas Hermanns, Jaime O. Herrera‐Caceres, Ardalan Ahmad, Michael A.S. Jewett, Girish S. Kulkarni   +6 more
doaj   +1 more source

A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections

International Journal of Infectious Diseases, 2022
: Objectives: This study aimed to evaluate the efficacy and safety of ceftolozane/tazobactam (C/T) plus metronidazole versus meropenem plus placebo for the treatment of complicated intra-abdominal infection (cIAI) in Chinese adult participants. Methods:
Yihong Sun, Jia Fan, Gang Chen, Xiaofei Chen, Xiaoling Du, Ye Wang, Hui Wang, Fang Sun, Matthew G. Johnson, Mekki Bensaci, Jennifer A. Huntington, Christopher J. Bruno   +11 more
doaj   +1 more source

An adaptive seamless phase II/III clinical trial design incorporating short-term endpoint information [PDF]

, 2011
Adaptive seamless phase II/III designs enable a clinical trial to be conducted in stages with the most promising of a number of experimental treatments selected on the basis of data observed in the first stage to continue along with the control ...
Stallard, Nigel, Nigel Stallard, Stallard Nigel   +2 more
core   +1 more source

An Improved Three-layer Analytic Hierarchy Process Model for Assessing Construction of Farmland Irrigation Canals in Tailings of Sand Mining

Guan'gai paishui xuebao, 2022
【Objective】 Constructing hydraulic engineering projects in tailings of sand mining faces many challenges that are absent in other areas. This paper presents a method to evaluate the risk and feasibility of building farmland irrigation channels in such ...
CUI Hongyan, ZHANG Endian, WANG Zhipeng, LI Qingfu   +3 more
doaj   +1 more source

Single and Multi-valued Neutrosophic Hypersoft set and Tangent Similarity Measure of Single valued Neutrosophic Hypersoft Sets [PDF]

Neutrosophic Sets and Systems, 2020
In this paper, we present a single-valued Neutrosophic Hypersoft set, multi-valued Neutrosophic Hypersoft set and tangent similarity measure for single-valued neutrosophic hypersoft sets and its properties.
Muhammad Saqlain , Naveed Jafar, Sana Moin, Muhammad Saeed, Said Broumi   +4 more
doaj   +1 more source

Part II – Analytical phase

Pathologica
Next-generation sequencing (NGS) has become a cornerstone of precision oncology, requiring standardized workflows in molecular pathology laboratories. The analytical phase, which includes all procedures from nucleic acid quantification to variant interpretation, plays a central role in ensuring the accuracy and clinical utility of molecular results ...
Elena, Guerini-Rocco, Konstantinos, Venetis, Silvia, Bessi, Simonetta, Buglioni, Caterina, Chiappetta, Dario, de Biase, Giovanna, De Maglio, Paolo, Graziano, Elisabetta, Macerola, Caterina, Marchiò, Elisa, Melucci, Mariantonia, Nacchio, Federica, Natoni, Andrea, Vingiani, Nicola, Fusco, Umberto, Malapelle, Giancarlo, Pruneri, Fabio, Pagni   +17 more
openaire   +5 more sources

Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management of irritable bowel syndrome in adults

Scientific Reports, 2019
The therapeutic effects of B. coagulans Unique IS2 have been well established in children with irritable bowel syndrome (IBS), but its efficacy in adults remain under reported. Thus, in this study the efficacy of B. coagulans Unique IS2 in the management
Ratna Sudha Madempudi, Jayesh J. Ahire, Jayanthi Neelamraju, Anirudh Tripathi, Satyavrat Nanal   +4 more
doaj   +1 more source

Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke [PDF]

, 2009
<p><b>Background and Purpose:</b> Clinical research into the treatment of acute stroke is complicated, is costly, and has often been unsuccessful.
Bolland, Kim, Lees, Kennedy J., Lihic, A., Bolland, K., Lihic, A., Lees, Kennedy, Ali, M., Lihic, Anela, Lees, K.R., Valdes-Marquez, E., Bolland, K., Whitehead, J., Ali, Myzoon, Valdes-Marquez, E., Whitehead, J., Ali, M., Whitehead, John, Lees, K., Valdés-Márquez, Elsa   +18 more
core   +1 more source