Results 31 to 40 of about 1,964,480 (312)

Visual Outcomes and Patient Satisfaction after Refractive Lens Exchange with a Single-Piece Diffractive Multifocal Intraocular Lens

open access: yesJournal of Ophthalmology, 2014
Purpose. To report visual outcomes and patient satisfaction after unilateral or bilateral refractive lens exchange (RLE) with a single-piece bifocal diffractive multifocal intraocular lens (MIOL). Methods.
John S. M. Chang   +3 more
doaj   +1 more source

A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints [PDF]

open access: yes, 2015
In an adaptive seamless phase II/III clinical trial interim analysis data are used for treatment selection, enabling resources to be focussed on comparison of more effective treatment(s) with a control.
Friede, Tim   +6 more
core   +1 more source

Visual Performance after Bilateral Implantation of a Four-Haptic Diffractive Toric Multifocal Intraocular Lens in High Myopes

open access: yesJournal of Ophthalmology, 2016
Background. The vision with diffractive toric multifocal intraocular lenses after cataract surgery in long eyes has not been studied previously. Objectives.
John S. M. Chang   +3 more
doaj   +1 more source

Phyto-Extracts in Wound Healing

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2013
Data generated through systematic investigation, carried out on the evaluation of phyto-extracts on wound healing research during the last 20 years have been compiled. About 450 plant species having wound healing properties have been identified.
Prasanta Kumar Ghosh, Anjali Gaba
doaj   +1 more source

Development of a Cationic Polymeric Micellar Structure with Endosomal Escape Capability Enables Enhanced Intramuscular Transfection of mRNA-LNPs

open access: yesVaccines
Background/Objectives: The endosomal escape of lipid nanoparticles (LNPs) is crucial for efficient mRNA-based therapeutics. Here, we present a cationic polymeric micelle (cPM) as a safe and potent co-delivery system with enhanced endosomal escape ...
Siyuan Deng   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Hawaii Deep Water Cable Program phase II-B : executive summary [PDF]

open access: yes, 1986
This Executive Summary for the Hawaii Deep Water Cable (HDWC) Program reviews work-to-date on the Program emphasizing the recently completed State-funded, Phase II-B tasks.
Mansur, J., Krasnick, George
core  

Fracture through previously asymptomatic lunotriquetral coalition: A case report

open access: yesJournal of Orthopaedic Reports
Background: Carpal coalition referes to the fusion of two or more carpal bones in the wrist. This has a prevalence of 0.1 % in Caucasian populations, where lunotriquetral coalition is reported as the most common type.
Ruchit Khera   +4 more
doaj   +1 more source

Chronic rhinosinusitis: correlation of symptoms with computed tomography scan findings

open access: yesThe Pan African Medical Journal, 2014
INTRODUCTION: Symptomatology, nasal endoscopy and Computerised Tomographic (CT) scan have been used to diagnose chronic rhinosinusitis. The value of disease severity score in the assessment of chronic rhinosinusitis has not been well investigated. Hence,
Enema Job Amodu   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

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