Results 251 to 260 of about 11,213,687 (295)
Some of the next articles are maybe not open access.
Pharmacogenetics of Phase I and Phase II Drug Metabolism
Current Pharmaceutical Design, 2010Genetic variation in the receptors and other intracellular targets that mediate the pharmacodynamic effects of drugs can affect therapeutic outcomes. However, at present greater knowledge is available concerning the extent of gene variation in drug metabolizing enzymes that determine drug pharmacokinetics and, in turn, drug efficacy and toxicity ...
Crettol, S., Petrovic, N., Murray, M.
openaire +2 more sources
2011
Functionalization reaction catalyzed by a phase I enzyme incorporates a functional group to a foreign compound, resulting in the formation of an intermediate metabolite. Many intermediates contain highly reactive chemical groups, which have the potential to react with cellular components (proteins, lipids, and DNA).
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Functionalization reaction catalyzed by a phase I enzyme incorporates a functional group to a foreign compound, resulting in the formation of an intermediate metabolite. Many intermediates contain highly reactive chemical groups, which have the potential to react with cellular components (proteins, lipids, and DNA).
openaire +2 more sources
Phase II: There is no Alternative!
2011Die „offizielle” Phase der Agenda 2010 dauert etwas mehr als 2 Jahre, bevor die rot-grune Koalition nach der verlorenen Landtagswahl 2005 in NRW von Bundeskanzler Schroder fur beendet erklart wird. Der Regierungschef versucht in der Agenda-Rede, den sozialpolitischen Kurs in auf Sachzwange verweisenden Satzen zu legitimieren.
Simon Hegelich +2 more
openaire +1 more source
2010
Abstract : The BAMS (Broad Area Maritime Surveillance UAS) will be the Navy's next-generation surveillance platform, able to collect far more data than it can send. The data is not of equal value, and the determination of what is valuable dynamically changes during a mission.
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Abstract : The BAMS (Broad Area Maritime Surveillance UAS) will be the Navy's next-generation surveillance platform, able to collect far more data than it can send. The data is not of equal value, and the determination of what is valuable dynamically changes during a mission.
openaire +1 more source
Phase transitions in 2D materials
Nature Reviews Materials, 2021Wenbin Li, Ju Li, Xiaofeng Qian
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Two-dimensional diamonds from sp2-to-sp3 phase transitions
Nature Reviews Materials, 2022Martin Rejhon +2 more
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