Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Phase transitions in project scheduling. [PDF]
The analysis of the complexity of combinatorial optimization problems has led to the distinction between problems which are solvable in a polynomially bounded amount of time (classified in P) and problems which are not (classified in NP).
De Reyck, B, Herroelen, Willy
core
A novel swarm-based algorithm for phase unwrapping [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2014.O correto funcionamento de tubulações subterrâneas para o transporte de gás e petróleo depende de ...
Maciel, Lucas da Silva
core
Sigmoid-Function-Based Adaptive Pelican Optimization Algorithm for Global Optimization
This paper introduces the Sigmoid-function-based Adaptive Pelican Optimization Algorithm (MPOA), an enhanced version of the traditional Pelican Optimization Algorithm (POA) aimed at improving the POA's performance.
A. F. S. Yussif +2 more
doaj +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Optimization of pressurized liquid extraction using a multivariate chemometric approach and comparison of solid phase extraction cleanup steps for the determination of polycyclic aromatic hydrocarbons in mosses [PDF]
A factorial design was used to optimize the extraction of polycyclic aromatic hydrocarbons (PAHs) from mosses, plants used as biomonitors of air pollution.
Foan, Louise, Simon, Valérie
core +1 more source
Heterogeneous-IRS-Assisted Millimeter-Wave Systems: Element Position and Phase Shift Optimization
Intelligent reflecting surfaces (IRSs) have attracted extensive attention in the design of future communication networks. However, their large number of reflecting elements still results in non-negligible power consumption and hardware costs.
Weibiao Zhao +4 more
doaj +1 more source
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Retrodictively optimal localizations in phase space [PDF]
In a previous paper it was shown that the distribution of measured values for a retrodictively optimal simultaneous measurement of position and momentum is always given by the initial state Husimi function. This result is now generalised to retrodictively optimal simultaneous measurements of an arbitrary pair of rotated quadratures x_theta1 and ...
openaire +2 more sources
Development and acceptability of behavioral interventions promoting mothers' brushing of pre-school children's teeth: The preparation phase of the multi-phase optimization strategy framework. [PDF]
Ihab M +3 more
europepmc +1 more source

