Results 51 to 60 of about 571,490 (277)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Regularization Methods for Phase Retrieval and Phase Contrast Tomography

Abstract and Applied Analysis, 2015
Phase contrast tomography is a high sensitivity medical imaging technique. Several regularization methods have been used in the literature to obtain stable solutions for the phase retrieval or the phase contrast tomography problems.
Bruno Sixou
doaj   +1 more source

GARLM: Greedy Autocorrelation Retrieval Levenberg–Marquardt Algorithm for Improving Sparse Phase Retrieval

Applied Sciences, 2018
The goal of phase retrieval is to recover an unknown signal from the random measurements consisting of the magnitude of its Fourier transform. Due to the loss of the phase information, phase retrieval is considered as an ill-posed problem.
Zhuolei Xiao, Yerong Zhang, Kaixuan Zhang, Dongxu Zhao, Guan Gui   +4 more
doaj   +1 more source

A Parameter Refinement Method for Ptychography Based on Deep Learning Concepts

Condensed Matter, 2021
X-ray ptychography is an advanced computational microscopy technique, which is delivering exceptionally detailed quantitative imaging of biological and nanotechnology specimens, which can be used for high-precision X-ray measurements.
Francesco Guzzi, George Kourousias, Alessandra Gianoncelli, Fulvio Billè, Sergio Carrato   +4 more
doaj   +1 more source

Phase Retrieval via Randomized Kaczmarz: Theoretical Guarantees

, 2017
We consider the problem of phase retrieval, i.e. that of solving systems of quadratic equations. A simple variant of the randomized Kaczmarz method was recently proposed for phase retrieval, and it was shown numerically to have a computational edge over ...
Tan, Yan Shuo, Vershynin, Roman
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Multi frame holograms batched optimization for binary phase spatial light modulators

Scientific Reports
Phase retrieval methods used in computer generated holograms such as Gerchberg-Saxton and gradient descent give results which are prone to noise and other defects.
Jinze Sha, Antoni Wojcik, Benjamin Wetherfield, Jianghan Yu, Timothy D. Wilkinson   +4 more
doaj   +1 more source

Higher Order Transport of Intensity Equation Methods: Comparisons and Their Hybrid Application for Noise Adaptive Phase Imaging

IEEE Photonics Journal, 2019
As a non-interferometric method, the transport of intensity equation (TIE) method suits for quantitative phase imaging with the commercial microscope platform, especially those higher order TIE approaches which can realize precise phase retrieval by ...
Junbao Hu, Qi Wei, Yan Kong, Zhilong Jiang, Liang Xue, Fei Liu, Dug Young Kim, Cheng Liu, Shouyu Wang   +8 more
doaj   +1 more source

Phase retrieval and saddle-point optimization

, 2007
Iterative algorithms with feedback are amongst the most powerful and versatile optimization methods for phase retrieval. Among these, the hybrid input-output algorithm has demonstrated practical solutions to giga-element nonlinear phase retrieval ...
Bauschke, Bauschke, Chapman, Chapman, Chen, Elser, Elser, Elser, Fienup, Fienup, Fienup, Gerchberg, Isernia, Levi, Luke, Luke, Marchesini, Marchesini, Miao, Miao, Oszlányi, Pfeifer, Powell, Shapiro, Stefano Marchesini, Youla   +25 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source