Results 51 to 60 of about 173,735 (257)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Linear phase retrieval for real-time adaptive optics [PDF]
Journal of the European Optical Society-Rapid Publications, 2013 We developed a fast phase retrieval algorithm that is suitable for real-time applications such as adaptive optics. The phase retrieval model is developed by linearising the pupil function in the approximation of small aberrations and is valid for low-NA ...
Polo A. +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Photonics, 2023 In-line X-ray phase contrast imaging, which is simple to experiment with, provides significantly higher sensitivity, compared to conventional X-ray absorption imaging.
Bei Yu +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Ptychographic phase retrieval by proximal algorithms
New Journal of Physics, 2020 We derive a set of ptychography phase-retrieval iterative engines based on proximal algorithms originally developed in convex optimization theory, and discuss their connections with existing ones.
Hanfei Yan
doaj +1 more source
Phase Retrieval for Nilpotent Groups
Journal of Fourier Analysis and Applications, 2023 AbstractWe study the phase retrieval property for orbits of general irreducible representations of nilpotent groups, for the classes of simply connected Lie groups, and for finite groups. We prove by induction that in the Lie group case, all irreducible representations do phase retrieval. For the finite group case, we mostly focus on p-groups. Here our
Hartmut Führ, Vignon Oussa
openaire +4 more sources
Geometry of the phase retrieval problem [PDF]
Inverse Problems, 2020 Abstract One of the most powerful approaches to imaging at the nanometer length scale is coherent diffraction imaging using x-ray sources. For amorphous (non-crystalline) samples, raw data collected in the far-field can be interpreted as the modulus of the two-dimensional continuous Fourier transform of the ...
Alexander H Barnett +3 more
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source