Results 41 to 50 of about 762,865 (262)

Digital filtering of square signals of chains' vector analizers

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
An algorithm for the use of digital filtering to the sine and cosine components of the quadrature signal in vector network analyzer is presented. Filters used for calibration and measuring stages to the original signals in volts and end measurements ...
D. A. Kondrashov   +3 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Measurement of electrodynamic characteristics of flat metal gratings in the teraherz range [PDF]

open access: yesРадиофизика и электроника, 2019
Subject and purpose. The terahertz frequency range now attracts much attention of researchers and consumers in connection with the wide possibilities of using it for solving a number of problems in science, technology and medicine.
M.I. Dzyubenko   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dynamical feedback between circadian clock and sucrose availability explains adaptive response of starch metabolism to various photoperiods

open access: yesFrontiers in Plant Science, 2013
Plants deal with resource management during all their life. During the day they feed on photosynthetic carbon, sucrose, while storing a part into starch for night use. Careful control of carbon partitioning, starch degradation and sucrose export rates is
Francois Gabriel Feugier, Akiko eSatake
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Melatonin and adjustment to phase shift [PDF]

open access: yesJournal of Sleep Research, 1995
SUMMARY  The pineal hormone melatonin has clear circadian phase‐shifting effects in humans which have recently been formalized as a phase response curve. Its potential use in circadian rhythm disorders has been investigated in field studies of jet lag and shift work and in simulated phase shift. A substantial amount of information indicates that in the
, Arendt   +4 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Development and Characterization of an Asymmetric MZI Temperature Sensor Using Polymer Waveguides for Extended Temperature Measurement Scopes

open access: yesPhotonics
To meet diverse industrial needs, temperature sensors with a wide measurement range have become a key element. In this paper, we propose an asymmetric Mach–Zehnder interferometer (MZI) temperature sensor based on polymer optical waveguides.
Fumin Liu   +3 more
doaj   +1 more source

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