Results 41 to 50 of about 5,860,039 (255)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Shift work: An occupational health and safety hazard [PDF]

open access: yes, 2003
Shift work is a major feature of modern work practices. It involves individuals working at times considered unconventional for most workers, such as at night.
Buxton, Sandra
core  

Dynamical feedback between circadian clock and sucrose availability explains adaptive response of starch metabolism to various photoperiods

open access: yesFrontiers in Plant Science, 2013
Plants deal with resource management during all their life. During the day they feed on photosynthetic carbon, sucrose, while storing a part into starch for night use. Careful control of carbon partitioning, starch degradation and sucrose export rates is
Francois Gabriel Feugier, Akiko eSatake
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Measurement of electrodynamic characteristics of flat metal gratings in the teraherz range [PDF]

open access: yesРадиофизика и электроника, 2019
Subject and purpose. The terahertz frequency range now attracts much attention of researchers and consumers in connection with the wide possibilities of using it for solving a number of problems in science, technology and medicine.
M.I. Dzyubenko   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Development and Characterization of an Asymmetric MZI Temperature Sensor Using Polymer Waveguides for Extended Temperature Measurement Scopes

open access: yesPhotonics
To meet diverse industrial needs, temperature sensors with a wide measurement range have become a key element. In this paper, we propose an asymmetric Mach–Zehnder interferometer (MZI) temperature sensor based on polymer optical waveguides.
Fumin Liu   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Frequency quantization in first-order digital phase-locked loops with frequency-modulated input [PDF]

open access: yes, 2007
Presented at the International Workshop on Nonlinear Maps and their Applications (NOMA '07), INSA, Toulouse, December 13-14, 2007Frequency granularity in a digital phase-locked loop arises from quantization in the number-controlled oscillator which ...
Tertinek, Stefan   +2 more
core   +1 more source

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