Results 51 to 60 of about 762,865 (262)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Modeling Movement Stability of Machine-Tractor Units Based on Modular Type Tractor
The object of the present research is a machine-tractor unit based on a tractor consisting of an energy (high-energy tractor—EM) and a technological (additional traction axle—TM) module.
Volodymyr Nadykto +7 more
doaj +1 more source
Noise in phase shifting interferometry [PDF]
We present a theoretical analysis to estimate the amount of phase noise due to noisy interferograms in Phase Shifting Interferometry (PSI). We also analyze the fact that linear filtering transforms corrupting multiplicative noise in Electronic Speckle Pattern Interferometry (ESPI) into fringes corrupted by additive gaussian noise. This fact allow us to
Quiroga Mellado, Juan Antonio +4 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Quantum Private Comparison Based on Four-Particle Cluster State
A quantum private comparison (QPC) protocol enables two parties to securely compare their private data without disclosing the actual values to one another, utilizing quantum mechanics to maintain confidentiality.
Min Hou, Yue Wu
doaj +1 more source
The use of a winding step of two slots attempts to strike a balance between traditional distributed windings and fractional slot concentrated windings.
Markus Harke
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
New Phase Shifting Algorithms Insensitive to Linear Phase Shift Errors
This article describes and analyses multistep algorithms for evaluating of the wave field phase in interferometric measurements using the phase shifting technique.
J. Novák
doaj
A Review of Solid-State LiDAR Principles and Metasurface-Based LiDAR Sensors
Light Detecting and Ranging (LiDAR) has been a promising solution for autonomous vehicles. For beam-steering mechanisms, solid-state LiDAR with microelectromechanical systems (MEMS) and optical phased arrays (OPAs) have demonstrated robust and compact ...
Elif Demirbas +6 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

