Results 101 to 110 of about 986,142 (266)

Thermophysical properties and high temperature properties of Sc2O3 doped ZrO2 thermal barrier coating ceramic materials

Cailiao gongcheng
8%（mass fraction）Y2O3 partially stabilized zirconia （8YSZ） is a currently commonly-used top-coat material for thermal barrier coatings （TBCs） applied to turbine blades in aero-engines.
LIU Liang, CHANG Zhendong, WANG Zhigang, MU Rende, CAI Yan, XIE Min, PENG Xiao, SHU Xiaoyong   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

On the Solidification and Phase Stability of Re-Bearing High-Entropy Superalloys with Hierarchical Microstructures

Metals
This study presents the design and microstructural investigation of a single-crystal (SX) Re-bearing high-entropy superalloy (HESA-X1) featuring a thermally stable γ–γ′–γ hierarchical microstructure. The alloy exhibits FCC γ nanoparticles embedded within
Wei-Che Hsu, Takuma Saito, Mainak Saha, Hideyuki Murakami, Taisuke Sasaki, An-Chou Yeh   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Fluorophenylalkylamine passivation of α-FAPbI3 for high-performance and air-stable photodetectors

Nano Research
Formamidinium–lead triiodide (FAPbI3) shows strong potential for high-performance photodetectors owing to its narrow band gap and superior thermal stability. However, fabrication of pure-phase α-FAPbI3 via a simple method remains challenging.
Mengxuan Wang, Yunjie Lou, Xintao Bai, Ziqiu Ren, Yanlin Song, Zhenkun Gu   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Laser Remelting-Induced Microstructure Refinement and Strengthening of (TaWZrHf)₉₅Y₅ Refractory High-Entropy Alloy

Journal of Manufacturing and Materials Processing
A novel (TaWZrHf)95Y5 refractory high-entropy alloy (RHEA) matrix was fabricated via vacuum hot pressing (VHP) sintering and subsequently modified through laser remelting (LR) surface treatment.
Chuanbing Huang, Junnan Jin, Yonghui Sun, Hao Lan, Weigang Zhang   +4 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Phase Stability in Rare‐Earth‐Doped Apatites: A Machine Learning Approach

Advanced Intelligent Systems
The study examines thermal behavior and phase stability of rare‐earth‐doped apatites (cerium, samarium, and holmium ions) between 25 °C and 1200 °C.
Geeta Sharma, Sarathkumar Loganathan, Evangelos Daskalakis, Eric K. Barimah, Simon Strafford, Animesh Jha   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source