Results 71 to 80 of about 670,855 (319)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Across the Boundary: The Formalization of the Interface Between Episodic Memory and Narrow Syntax Computation of Human Language

open access: yesBiolinguistics
A growing number of studies indicate that the hippocampus plays an essential role in language processing as well as episodic memory. However, there is no consensus on how it is engaged in both domains and how it connects the two domains.
Edward Ruoyang Shi
doaj   +1 more source

Theory of Solid-Phase Microextraction [PDF]

open access: yesJournal of Chromatographic Science, 2000
The main objective of this contribution is to describe the fundamental concepts associated with solid-phase microextraction (SPME). Theory provides insight when developing SPME methods and identifies parameters for rigorous control and optimization. A mathematical model has been developed to understand the principal processes of SPME by applying basic ...
openaire   +2 more sources

Shock dynamics of phase diagrams

open access: yes, 2014
A thermodynamic phase transition denotes a drastic change of state of a physical system due to a continuous change of thermodynamic variables, as for instance pressure and temperature.
Moro, Antonio
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Density functional theory for chiral nematic liquid crystals

open access: yes, 2014
Even though chiral nematic phases were the first liquid crystals experimentally observed more than a century ago, the origin of the thermodynamic stability of cholesteric states is still unclear.
Sub Soft Condensed Matter   +8 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Information theory bounds on randomness-based phase transitions

open access: yesSciPost Physics
We introduce a new perspective on the connection between many-body physics and information theory. We study phase transitions in models with randomness, such as localization in disordered systems, or random quantum circuits with measurements.
Noa Feldman, Niv Davidson, Moshe Goldstein
doaj   +1 more source

New phase transitions in Chern–Simons matter theory

open access: yesNuclear Physics B, 2016
Applying the machinery of random matrix theory and Toeplitz determinants we study the level k, U(N) Chern–Simons theory coupled with fundamental matter on S2×S1 at finite temperature T. This theory admits a discrete matrix integral representation, i.e. a
Ali Zahabi
doaj   +1 more source

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