Results 61 to 70 of about 6,058,423 (308)

Pulmonary tuberculosis case detection in South Sudan

South Sudan Medical Journal, 2012
Background: The National Tuberculosis (TB) Control Programme in South Sudan was created in 2006, and non-governmental organizations (NGOs) are its main implementers. Pulmonary tuberculosis (PTB) is a major public health threat.
David L. Lukudu
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Technologies for African Agricultural Transformation (TAAT) celebrates 143 interventions in 132 sites across Africa: Updates 2018, Issue 001

, 2023
The Technologies for African Agricultural Transformation (TAAT) Program was initiated by the African Development Bank (AfDB) as part of its Feed Africa Initiative.
Technologies for African Agricultural Transformation
core   +1 more source

Martensitic Transformation Induced by B2 Phase Precipitation in an Fe-20 Ni-4.5 Al-1.0 C Alloy Steel Following Solution Treatment and Subsequent Isothermal Holding

Metals
Phase transformations significantly influence the mechanical properties of Fe-based alloys, making their understanding essential for the design of high-performance alloy materials.
Rosemary Chemeli Korir, Yen-Ting Huang, Wei-Chun Cheng   +2 more
doaj   +1 more source

Three-Phase Transformer

CoRR
48 pages, 20 figures, 23 tables.
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Deformation-assisted diffusion for the enhanced kinetics of dynamic phase transformation

Materials Research Letters, 2018
Comparison on the kinetics of two different phase transformations, including phase transformation after deformation and phase transformation during deformation (i.e.
Lijia Zhao, Nokeun Park, Yanzhong Tian, Akinobu Shibata, Nobuhiro Tsuji   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source