Results 71 to 80 of about 4,648,765 (293)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Phase Transformation and Physical Properties of A lN-Co Film

open access: yes, 2013
Annealing techniques were applied to induce phase transformations and phase separations in AlN-Co thin films with various Co contents and AlN-Co multilayer thin films with various layer-thicknesses were prepared by a two-facing-target type DC sputtering ...
길상철, 오창섭
core  

The development of a multi-frequency electromagnetic instrument for monitoring the phase transformation of hot strip steel. [PDF]

open access: yes, 2005
This paper describes the development of an instrument to analyze the phase transformations of hot strip steel using an electromagnetic sensor. The sensor exploits variations in the electrical conductivity and magnetic permeability of the steel to monitor
Dickinson, S. J.   +4 more
core   +4 more sources

Theoretical study on thermal and structural phenomena in thin elements heated by a laser beam

open access: yesArchives of Mechanics, 2015
This paper concerns the mathematical and numerical modelling of thermal phenomena and phase transformations in the solid state accompanying laser heating processes.
M. Kubiak, W. Piekarska, R. Parkitny
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Kinetics of sigma phase formation in a Duplex Stainless Steel

open access: yesMaterials Research, 2009
This work determines the kinetics of sigma phase formation in UNS S31803 Duplex Stainless Steel (DSS), describing the phase transformations that occur in isothermal aging between 700 and 900 ºC for time periods up to 1032 hours, allowing the ...
Rodrigo Magnabosco
doaj   +1 more source

Phase transformation in barium tetraborate

open access: yesJournal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1969
Orthorhombic BaB8O13 (a = 8.550, b = 17.352, c= 13.211 Å, D = 2.927 g/cm3 at 25 °C) transforms reversibly at 700 °C to a high-temperature tetragonal form (a = 8.629, c = 13.252 Å, D = 2.906 g/cm3) stable from 700 °C to the congruent melting point (889 °C) of the compound. The transition is rapid and probably displacive in character.
C R, Robbins, E M, Levin
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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