Results 61 to 70 of about 826,806 (318)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Baryogenesis at a lepton-number-breaking phase transition

open access: yesJournal of High Energy Physics, 2017
We study a scenario in which the baryon asymmetry of the universe arises from a cosmological phase transition where lepton-number is spontaneously broken.
Andrew J. Long   +2 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Phase Transitions in Phase Retrieval [PDF]

open access: yes, 2015
Consider a scenario in which an unknown signal is transformed by a known linear operator, and then the pointwise absolute value of the unknown output function is reported. This scenario appears in several applications, and the goal is to recover the unknown signal -- this is called phase retrieval. Phase retrieval has been a popular subject of research
openaire   +3 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Cosmological phase transition of spontaneous confinement

open access: yesJournal of High Energy Physics, 2020
The dynamics of a cosmological (de)confinement phase transition is studied in nearly conformally invariant field theories, where confinement is predominantly spontaneously generated and associated with a light “dilaton” field.
Kaustubh Agashe   +4 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Criterion for Many-Body Localization-Delocalization Phase Transition

open access: yesPhysical Review X, 2015
We propose a new approach to probing ergodicity and its breakdown in one-dimensional quantum many-body systems based on their response to a local perturbation.
Maksym Serbyn   +2 more
doaj   +1 more source

Phase transitions in the Universe [PDF]

open access: yesContemporary Physics, 1998
31 pages, LaTeX, 10 figures, 8 provided (7 EPS + 1 PS). Uses psfig.tex. Invited article for ``Contemporary Physics''
openaire   +4 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

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