Results 81 to 90 of about 802,277 (269)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Numerical Tools for Electroweak Phase Transition
UniverseThe electroweak phase transition serves as a crucial portal to explore physics beyond the Standard Model, with profound implications for gravitational waves, baryogenesis, dark matter, and vacuum stability.
Xinran Zeng, Yang Zhang
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Quantum phase transition of infrared radiation
Journal of High Energy PhysicsWe describe a phase transition of infrared radiation, driven by quantum fluctuations, which takes place at the boundary of (the conformal diagram of) Minkowski spacetime.
Bartosz Biadasiewicz, Wojciech Dybalski
doaj +1 more source
Annalen der Physik, 2000 AbstractThe sequence of phase transitions during the hot history of the universe is followed within a phenomenological framework. Particular emphasis is put on the QCD confinement transition, which is at reach under earth laboratory conditions. A tepid inflationary scenario on the GUT scale with bubble growth at moderate supercooling is discussed.
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Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
The chiral phase transition [PDF]
Nuclear Physics A, 1996 13 pages, 9 PS figures, to appear in QM96 proceedings (Nucl. Phys. A)
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Photonic topological phase transition on demand
Nanophotonics, 2019 On-demand, switchable phase transitions between topologically nontrivial and trivial photonic states are demonstrated. Specifically, it is shown that the integration of a two-dimensional array of coupled ring resonators within a thermal heater array ...
Kudyshev Zhaxylyk A. +3 more
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Phase Transition and Fractals [PDF]
Progress of Theoretical Physics, 1983 Summary: We give a geometrical interpretation of critical phenomena, particularly of the scaling relations on critical exponents, by the use of statistical fractal dimensionality. We also discuss the relation between this geometrical interpretation and the finite size scaling theory.
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