Results 61 to 70 of about 802,277 (269)
13 pages, 3 ...
Ke Xu 0001, Wei Li 0022
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Baryogenesis via leptonic CP-violating phase transition
We propose a new mechanism to generate a lepton asymmetry based on the vacuum CP-violating phase transition (CPPT). This approach differs from classical thermal leptogenesis as a specific seesaw model, and its UV completion, need not be specified.
Silvia Pascoli +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Negative Thermal Expansion Near the Precipice of Structural Stability in Open Perovskites
Negative thermal expansion (NTE) describes the anomalous propensity of materials to shrink when heated. Since its discovery, the NTE effect has been found in a wide variety of materials with an array of magnetic, electronic and structural properties.
Connor A. Occhialini +7 more
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Phase transitions in the Universe [PDF]
31 pages, LaTeX, 10 figures, 8 provided (7 EPS + 1 PS). Uses psfig.tex. Invited article for ``Contemporary Physics''
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Skyrmion crystals: Dynamics and phase transition
We study a crystal of skyrmions generated on a square lattice using a ferromagnetic exchange interaction and a Dzyaloshinskii-Moriya interaction between nearest-neighbors under an external magnetic field.
H. T. Diep +2 more
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These are notes for lectures delivered at the NATO ASI on Dynamics in Leiden, The Netherlands, in July 1998. The main concepts relating to quantum phase transitions are explained, using the paramagnet-to-ferromagnet transition of itinerant electrons as the primary example. Some aspects of metal-insulator transitions are also briefly discussed.
Belitz, D., Kirkpatrick, T. R.
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

