Results 131 to 140 of about 9,597,779 (345)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Wilson loops in antisymmetric representations from localization in supersymmetric gauge theories
, 2017 Large-N phase transitions occurring in massive N=2 theories can be probed by Wilson loops in large antisymmetric representations. The logarithm of the Wilson loop is effectively described by the free energy of a Fermi distribution and exhibits second ...
Russo, Jorge, Zarembo, Konstantin
core +1 more source
Dynamical phase transition in the simplest molecular chain model [PDF]
, 2014 V. A. Malyshev, S. A. Muzychka
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Phase Transitions in Nonlinear Filtering
, 2014 It has been established under very general conditions that the ergodic properties of Markov processes are inherited by their conditional distributions given partial information.
Rebeschini, Patrick, van Handel, Ramon
core +1 more source
Revisiting the nonequilibrium phase transition of the triplet-creation model [PDF]
, 2006 G. O. Cardozo, J. F. Fontanari
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Phase Transitions in "Small" systems
, 1999 Traditionally, phase transitions are defined in the thermodynamic limit only. We discuss how phase transitions of first order (with phase separation and surface tension), continuous transitions and (multi)-critical points can be seen and classified for ...
Gross, D. H. E., Votyakov, E.
core +1 more source
CHIRAL MAGNETIC EFFECT AND QCD PHASE TRANSITIONS WITH EFFECTIVE MODELS [PDF]
, 2011 WEI-JIE FU, YU-XIN LIU, YUE-LIANG WU
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source