Results 111 to 120 of about 3,197,248 (349)

Computational learning of the conditional phase-type (C-Ph) distribution: Learning C-Ph distributions

, 2014
This paper presents a new algorithm for learning the structure of a special type of Bayesian network. The conditional phase-type (C-Ph) distribution is a Bayesian network that models the probabilistic causal relationships between a skewed continuous ...
Shaw, Barry, Marshall, Adele H.
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Precipitate Phases of Electron Beam Welded Joint in Superalloy Dissimilar Materials

Journal of Aeronautical Materials, 2018
The precipitate phases of electron beam welded joint in GH141/GH907 superalloy dissimilar materials were studied by scanning electron microscopy (SEM), transmission electron microscope (TEM) and energy dispersive spectrometer (EDS).
LIU Jin, ZHAO Zhiyi
doaj   +1 more source

Approximation of Cumulative Distribution Functions by Bernstein Phase-Type Distributions

Performance Evaluation
The inclusion of generally distributed random variables in stochastic models is often tackled by choosing a parametric family of distributions and applying fitting algorithms to find appropriate parameters. A recent paper proposed the approximation of probability density functions (PDFs) by Bernstein exponentials, which are obtained from Bernstein ...
András Horváth, Illés Horváth, Marco Paolieri, Miklós Telek, Enrico Vicario   +4 more
openaire   +2 more sources

Sequence Discrimination Using Phase-Type Distributions [PDF]

, 2006
We propose in this paper a novel approach to the classification of discrete sequences. This approach builds a model fitting some dynamical features deduced from the learning sample. These features are discrete phase-type (PH) distributions. They model the first passage times (FPT) between occurrences of pairs of substrings.
Jérôme Callut, Pierre Dupont
openaire   +1 more source

Advanced modelling and visualisation of liquid-liquid separations of complex sample components, with variable phase distribution and mode of operation

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is about liquid-liquid chromatography modelling.
De Folter, Jozefus Johannes Martinus
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Modelling of non‐Markovian queuing systems

Technological and Economic Development of Economy, 2006
The purpose of this paper is to suggest a method and software for evaluating queuing approximations. A numerical queuing model with priorities is used to explore the behaviour of exponential phase‐type approximation of service‐time distribution.
Giedrius Mickevičius, Eimutis Valakevičius   +1 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source