Results 121 to 130 of about 15,414,698 (300)
A two-stage approach to the joint analysis of longitudinal and survival data utilising the Coxian phase-type distribution. [PDF]
Stat Methods Med Res, 2018 Donnelly C +3 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2012 The paper considers the distinctive features of different types of single-phase damage in the distribution networks. By results of researches the algorithm is developed for definition of type of single-phase damage on the basis of the information on ...
E. V. Kalentionok, Yu. A. Mazurek
doaj
StatsThis study focuses on forecasting and optimizing the performance of a real-world object modelled by a multi-server queueing system that processes two types of users: primary (new) users and repeating users.
Alexander N. Dudin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Nakagami-M Phase-Envelope Joint
, 2008 Introduction: When the Nakagami-m envelope distribution was proposed [1], no information on the phase distribution of the corresponding signal was provided.
Distribution Yacoub Fraidenraich
core
The Prediction’s Trend of Graft Survival in Renal Transplantation with Chronic Allograft Dysfunction
مجله اپیدمیولوژی ایران, 2010 Background & Objective: Clinically Chronic Allograft Dysfunction (CAD) is characterized by a progressive decline in Glomerular Filtration Rate (GFR) over time, the pattern of disease progression determined by the five-stage model.
HR Khalkhali +3 more
doaj
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source