Results 111 to 120 of about 1,372,433 (300)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

A Single-Sensor Approach for Noninvasively Tracking Phase Velocity in Tendons during Dynamic Movement. [PDF]

Micromachines (Basel), 2023
Schmitz DG, Thelen DG, Cone SG.
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Anisotropic media with singular slowness surfaces

Геофизический журнал
It is proved that if an anisotropic medium has an open set of singular directions, then this medium has two slowness surfaces that completely coincide. The coinciding slowness surfaces form one double singular slowness surface.
Yu.V. Roganov, A. Stovas, V.Yu. Roganov
doaj   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Thermodynamic effects of torsional surface waves in heterogeneous and homogeneous elastic semi-infinite substratum

Applied and Computational Mechanics
The prime goal of the study is to investigate the relevance of torsional surface wave propagation in a thermally conducting heterogeneous (functionally graded) semi-infinite medium.
Haldar N., Pradhan N., Samal S. K., Saha S., Pramanik S.   +4 more
doaj   +1 more source

Phase Velocity Estimation With Expanded Bandwidth in Viscoelastic Phantoms and Tissues. [PDF]

IEEE Trans Med Imaging, 2021
Kijanka P, Urban MW.
europepmc   +1 more source

Velocity Structure of Self-Similar Spherically Collapsed Halos

, 2010
Using a generalized self-similar secondary infall model, which accounts for tidal torques acting on the halo, we analyze the velocity profiles of halos in order to gain intuition for N-body simulation results.
Bertschinger, Edmund, Zukin, Phillip
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Wave propagation in a pipe conveying two phase flow

Acta Polytechnica
The study of wave propagation in pipes conveying a two-phase flow is of significant importance in various engineering applications, including the oil and gas, chemical, and nuclear industries.
Akintoye O. Oyelade, Adegboyega B. Ehinmowo, Oluwasola Oribayo, Yetunde O. Abiodun   +3 more
doaj   +1 more source