Results 91 to 100 of about 1,372,433 (300)

Phase separation and large deviations of lattice active matter

open access: yes, 2017
Off-lattice active Brownian particles form clusters and undergo phase separation even in the absence of attractions or velocity-alignment mechanisms. Arguments that explain this phenomenon appeal only to the ability of particles to move persistently in a
Klymko, Katherine   +2 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Calculation of Guided Wave Dispersion Characteristics Using a Three-Transducer Measurement System

open access: yesApplied Sciences, 2018
Guided ultrasonic waves are of significant interest in the health monitoring of thin structures, and dispersion curves are important tools in the deployment of any guided wave application.
Borja Hernandez Crespo   +2 more
doaj   +1 more source

Counterposed phase velocity and energy-transport velocity vectors in a dielectric-magnetic uniaxial medium

open access: yes, 2004
When a plane wave is launched from a plane surface in a linear, homogenous, dielectric-magnetic, uniaxial medium, we show that its phase velocity and the energy-transport velocity vectors can be counterposed (i.e., lie on different sides of the surface ...
Akhlesh Lakhtakia   +6 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tracing the Dark Matter Sheet in Phase Space

open access: yes, 2012
The primordial velocity dispersion of dark matter is small compared to the velocities attained during structure formation. The initial density distribution is close to uniform and it occupies an initial sheet in phase space that is single valued in ...
Abel   +58 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Twisting waves increase the visibility of nonlinear behaviour

open access: yesNew Journal of Physics, 2020
Nonlinear behaviour for acoustic systems is readily measured at high acoustic pressures in gasses or bulk materials. However, at low acoustic pressures nonlinear effects are not commonly observed.
Grace Richard   +5 more
doaj   +1 more source

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